SCHEMBL7523249

SCHEMBL7523249

O=C(O)COc1cccc2c1CCc1sc(SC(c3ccccc3)c3ccccc3Cl)nc1-2

nearest known ligand 0.39

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PTGIR P43119 11/20 0.39
CTSA P10619 6/20 0.35
PTGDR2 Q9Y5Y4 1/20 0.34
MEN1 O00255 1/20 0.34
POLB P06746 1/20 0.34
KMT2A Q03164 1/20 0.34
TBXA2R P21731 2/20 0.34
PTGDR Q13258 1/20 0.34
LMNA P02545 1/20 0.34
MAPT P10636 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7519310 0.91 PTGIR (0.43) PTGIRMEN1POLBKMT2ATBXA2R
SCHEMBL7526675 0.90 PTGIR (0.39) PTGIRCTSATBXA2RPTGDR
SCHEMBL7523906 0.90 PTGIR (0.39) PTGIRCTSATBXA2RPTGDR
SCHEMBL7524431 0.90 PTGIR (0.40) PTGIRPTGDR2TBXA2RPTGDR
SCHEMBL7526342 0.88 PTGIR (0.41) PTGIRPTGDR2TBXA2RPTGDR
SCHEMBL7522740 0.88 PTGIR (0.37) PTGIRPTGDR2MEN1POLBKMT2A
SCHEMBL7518608 0.87 PTGIR (0.40) PTGIRCTSAPTGDR2TBXA2RPTGDR
SCHEMBL7523179 0.87 PTGIR (0.40) PTGIRPTGDR2TBXA2RPTGDR
SCHEMBL7555836 0.86 PTGIR (0.41) PTGIRPTGDR2TBXA2RPTGDR
SCHEMBL7579116 0.85 PTGIR (0.37) PTGIRCTSAMEN1POLBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6417213-B2 ANTICOAGULANTS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2002-07-09 US disclosed
US-20020006944-A1 Tricyclic compounds, their production and use OHKAWA SHIGENORI (JP) 2002-01-17 US disclosed
US-6248766-B1 CARDIOVASCULAR DISORDERS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2001-06-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020006944-A1 Tricyclic compounds, their production and use CNR1, PTGER1, PTGDR PTGIR 11/4885CTSA 3256/4885PTGDR2 10/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.