SCHEMBL7524360

SCHEMBL7524360

CC(=O)CC(=O)NCC(=O)Nc1ccccc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.67
POLB P06746 1/20 0.56
PKM P14618 1/20 0.56
SCN1A P35498 1/20 0.54
SCN2A Q99250 1/20 0.54
SCN3A Q9NY46 1/20 0.54
KMT2A Q03164 5/20 0.53
MEN1 O00255 4/20 0.53
ALDH1A1 P00352 2/20 0.53
LMNA P02545 1/20 0.53
RAB9A P51151 1/20 0.53
NAPRT Q6XQN6 1/20 0.52
HSD17B10 Q99714 1/20 0.52
HDAC3 O15379 1/20 0.51
HDAC4 P56524 1/20 0.51
HDAC1 Q13547 1/20 0.51
HDAC7 Q8WUI4 1/20 0.51
HDAC2 Q92769 1/20 0.51
HDAC10 Q969S8 1/20 0.51
HDAC11 Q96DB2 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14914 0.87 MAPT (0.85) MAPTPOLBSCN1ASCN2ASCN3A
SCHEMBL9121361 0.87 MAPT (0.85) MAPTPOLBSCN1ASCN2ASCN3A
SCHEMBL6018459 0.85 NAPRT (0.61) MAPTPOLBPKMSCN1ASCN2A
Potassium SCHEMBL30309050 0.85 MAPT (0.82) MAPTPOLBSCN1ASCN2ASCN3A
Bromide SCHEMBL27974437 0.85 MAPT (0.82) MAPTPOLBSCN1ASCN2ASCN3A
SCHEMBL28996270 0.85 MAPT (0.82) MAPTPOLBSCN1ASCN2ASCN3A
SCHEMBL8849064 0.85 MAPT (0.82) MAPTPOLBSCN1ASCN2ASCN3A
Methane SCHEMBL28009609 0.85 MAPT (0.82) MAPTPOLBSCN1ASCN2ASCN3A
SCHEMBL587369 0.85 MAPT (0.82) MAPTPOLBSCN1ASCN2ASCN3A
Hydrochloric Acid SCHEMBL28406796 0.85 MAPT (0.82) MAPTPOLBSCN1ASCN2ASCN3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0823459-B1 Disazo pigment composition and printing ink DAINIPPON INK & CHEMICALS (JP) 2002-04-17 EP disclosed
US-5803962-A Disazo pigment composition and printing ink DAINIPPON INK AND CHEMICALS, INC. (JP) 1998-09-08 US disclosed
EP-0823459-A2 Disazo pigment composition and printing ink DAINIPPON INK AND CHEMICALS, INC. (JP) 1998-02-11 EP disclosed
EP-0064952-B1 MONOAZO DYESTUFFS CIBA-GEIGY AG (CH) 1985-07-24 EP disclosed
US-4473500-A Monoazo pigments derived from aminophthalimides and substituted acetoacetarylides or 2-hydroxy-3-naphthoylarylides CIBA-GEIGY CORPORATION (US) 1984-09-25 US disclosed
EP-0064952-A1 Monoazo dyestuffs CIBA-GEIGY AG (CH) 1982-11-17 EP disclosed