Diphenylamine

Diphenylamine

SCHEMBL7524565

c1c[nH]nn1.c1ccc(Nc2ccccc2)cc1

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 5/20 0.50
ALDH1A1 P00352 6/20 0.48
TDP1 Q9NUW8 5/20 0.48
TSHR P16473 4/20 0.48
ALOX12 P18054 3/20 0.48
L3MBTL1 Q9Y468 3/20 0.48
ALOX15 P16050 2/20 0.48
PTGS1 P23219 1/20 0.48
SLC6A2 P23975 1/20 0.48
MAPK1 P28482 1/20 0.48
PTGS2 P35354 1/20 0.48
HTR2B P41595 1/20 0.48
MAPT P10636 5/20 0.43
MEN1 O00255 5/20 0.43
KMT2A Q03164 5/20 0.43
AR P10275 1/20 0.43
LMNA P02545 3/20 0.41
CYP3A4 P08684 5/20 0.40
HPGD P15428 2/20 0.40
HTT P42858 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27753867 0.87 AURKA (0.46) MAPK1MAPTMEN1KMT2ALMNA
Phenylhydrazine SCHEMBL27512048 0.84 TDP1 (0.54) HSD17B10ALDH1A1TDP1TSHRALOX12
Biphenyl SCHEMBL1551538 0.80 NOTUM (0.44) ALDH1A1ALOX15MAPK1CYP1A2RAB9A
Benzene SCHEMBL487381 0.79
Benzene SCHEMBL28126191 0.79
Benzene SCHEMBL28097781 0.79
Naphthalene SCHEMBL4047989 0.78 CYP2A6 (0.40) ALDH1A1ALOX12L3MBTL1MAPTMEN1
Naphthalene SCHEMBL28993985 0.78 CYP2A6 (0.40) ALDH1A1ALOX12L3MBTL1MAPTMEN1
(Z)-1,2-Diphenylethene SCHEMBL5933870 0.77 CYP11B1 (0.47) ALDH1A1TSHRMEN1KMT2ALMNA
Phenol SCHEMBL1398374 0.77 CA12 (0.48) TDP1PTGS1SLC6A2PTGS2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108026470-A The lubricating composition of the new alkylation diphenylamine derivatives of triazole and the new alkylation diphenylamine derivatives containing the triazole 范德比尔特化学品有限责任公司 2018-05-11 CN disclosed
CN-108026467-A Improved antioxidant composition and lubricating composition containing the same 范德比尔特化学品有限责任公司 2018-05-11 CN disclosed
EP-1187894-A1 HIGH STRESS ELECTRICAL OIL ExxonMobil Research and Engineering Company (US) 2002-03-20 EP disclosed
WO-2000071648-A1 HIGH STRESS ELECTRICAL OIL EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2000-11-30 WO disclosed