Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.48 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 4/20 | 0.46 |
| ▸ | DRD3 | P35462 | 4/20 | 0.46 |
| ▸ | DRD4 | P21917 | 3/20 | 0.46 |
| ▸ | DRD2 | P14416 | 3/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.44 |
| ▸ | SCD | O00767 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7545031 | 1.00 | NPC1 (0.49) | NPC1ALDH1A1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL7542523 | 1.00 | NPC1 (0.49) | NPC1ALDH1A1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL7545697 | 1.00 | NPC1 (0.49) | NPC1ALDH1A1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL7541378 | 1.00 | NPC1 (0.49) | NPC1ALDH1A1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL7545313 | 1.00 | NPC1 (0.49) | NPC1ALDH1A1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL7546434 | 0.91 | HDAC6 (0.52) | NPC1ALDH1A1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL7547428 | 0.91 | HDAC6 (0.52) | NPC1ALDH1A1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL7548641 | 0.91 | HDAC6 (0.52) | NPC1ALDH1A1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL7548431 | 0.91 | HDAC6 (0.52) | NPC1ALDH1A1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL7541200 | 0.91 | HDAC6 (0.52) | NPC1ALDH1A1MAPTRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882716-B1 | PYRIDINECARBOXAMIDE DERIVATIVES | NISSHIN PHARMA INC (JP) | 2002-04-10 | — | — | EP | disclosed |
| US-6046201-A | Pyridinecarboxamide derivatives | NISSHIN FLOUR MILLING CO., LTD. (JP) | 2000-04-04 | — | — | US | disclosed |
| EP-0882716-A1 | PYRIDINECARBOXAMIDE DERIVATIVES | Nisshin Flour Milling Co., Ltd. (JP) | 1998-12-09 | — | — | EP | disclosed |