Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.80 |
| ▸ | CA4 | P22748 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | FYN | P06241 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL7721224 | 1.00 | CA1 (0.80) | CA1CA4LMNATSHRFFAR3 | |
| Acetic Acid SCHEMBL8679492 | 1.00 | CA1 (0.80) | CA1CA4LMNATSHRFFAR3 | |
| Acetic Acid SCHEMBL8504560 | 1.00 | CA1 (0.80) | CA1CA4LMNATSHRFFAR3 | |
| Acetic Acid SCHEMBL8325465 | 0.95 | CA1 (0.89) | CA1CA4LMNATSHRFFAR3 | |
| Acetic Acid SCHEMBL140521 | 0.95 | CA1 (0.89) | CA1CA4LMNATSHRFFAR3 | |
| Acetic Acid SCHEMBL25170206 | 0.90 | CA1 (0.80) | CA1CA4LMNATSHRFFAR3 | |
| Acetic Acid SCHEMBL25215531 | 0.90 | CA1 (0.80) | CA1CA4LMNATSHRFFAR3 | |
| Acetic Acid SCHEMBL21752943 | 0.90 | CA1 (0.80) | CA1CA4LMNATSHRFFAR3 | |
| Acetic Acid SCHEMBL25312642 | 0.90 | CA1 (0.80) | CA1CA4LMNATSHRFFAR3 | |
| Acetic Acid SCHEMBL21752948 | 0.90 | CA1 (0.80) | CA1CA4LMNATSHRFFAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11279799-B2 | Polyester resin, preparation method thereof, and resin molded article formed therefrom | SK CHEMICALS CO., LTD. (KR) | 2022-03-22 | — | — | US | disclosed |
| US-20210171706-A1 | POLYESTER RESIN, PREPARATION METHOD THEREOF, AND RESIN MOLDED ARTICLE FORMED THEREFROM | SK CHEMICALS CO., LTD. (KR) | 2021-06-10 | — | — | US | disclosed |
| EP-3395855-B1 | POLYESTER RESIN, METHOD FOR PRODUCING SAME, AND RESIN MOLDED PRODUCT FORMED THEREFROM | SK CHEMICALS CO LTD (KR) | 2021-03-31 | — | — | EP | disclosed |
| EP-3395855-A1 | POLYESTER RESIN, METHOD FOR PRODUCING SAME, AND RESIN MOLDED PRODUCT FORMED THEREFROM | SK Chemicals Co., Ltd. (KR) | 2018-10-31 | — | — | EP | disclosed |
| EP-3235915-A1 | METHOD FOR THE PRODUCTION OF NANOSTRUCTURED SKUTTERUDITES OF THE COSB3 TYPE | Acondicionamiento Tarrasense (Centro Tecnológico LEITAT) (ES) | 2017-10-25 | — | — | EP | disclosed |
| EP-2722352-A1 | METHOD FOR MANUFACTURING BIOMASS-DERIVED POLYESTER AND BIOMASS-DERIVED POLYESTER | Toray Industries, Inc. (JP) | 2014-04-23 | — | — | EP | disclosed |
| US-20120322970-A1 | BIOMASS RESOURCE-DERIVED POLYESTER AND METHOD FOR PRODUCING SAME | TORAY INDUSTRIES, INC. (JP) | 2012-12-20 | — | — | US | disclosed |
| US-6437051-B2 | IMPACT STRENGTH, ELONGATION | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2002-08-20 | — | — | US | disclosed |
| US-20020019494-A1 | Graft copolymer of syndiotatic styrene copolymer | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2002-02-14 | — | — | US | disclosed |
| EP-1013671-B1 | Functionalized syndiotactic styrene/para-alkylstyrene copolymer | IND TECH RES INST (TW) | 2001-11-28 | — | — | EP | disclosed |
| US-6180725-B1 | Resin compositions for electric circuit boards | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2001-01-30 | — | — | US | disclosed |
| EP-1013671-A1 | Functionalized syndiotactic styrene/para-alkylstyrene copolymer | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2000-06-28 | — | — | EP | disclosed |
| EP-1010711-A1 | Graft copolymer of syndiotactic styrene copolymer | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2000-06-21 | — | — | EP | disclosed |
| US-6015862-A | GRAFT COPOLYMERS | THE PENN STATE RESEARCH FOUNDATION (US) | 2000-01-18 | — | — | US | disclosed |
| US-5866659-A | Functionalized α-olefin/para-alkylstryne copolymers | THE PENN STATE RESEARCH FOUNDATION (US) | 1999-02-02 | — | — | US | disclosed |
| US-5543484-A | CRYSTAL STRUCTURE, TOUGHNESS, HIGH DENSITY | THE PENN STATE RESEARCH FOUNDATION (US) | 1996-08-06 | — | — | US | disclosed |