Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 15/20 | 0.68 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.51 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.51 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.51 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.50 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.50 |
| ▸ | CDK1 | P06493 | 2/20 | 0.50 |
| ▸ | CDK4 | P11802 | 2/20 | 0.50 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.50 |
| ▸ | CCND1 | P24385 | 2/20 | 0.50 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.50 |
| ▸ | CDK2 | P24941 | 2/20 | 0.50 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.50 |
| ▸ | FLT3 | P36888 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5088983 | 1.00 | ADORA2A (0.68) | ADORA2AADORA3ADORA2BADORA1CCNB2 | |
| SCHEMBL5088994 | 1.00 | ADORA2A (0.68) | ADORA2AADORA3ADORA2BADORA1CCNB2 | |
| SCHEMBL7222053 | 0.92 | ADORA2A (0.69) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL7222050 | 0.92 | ADORA2A (0.69) | ADORA2AADORA3ADORA2BADORA1 | |
| Hydrochloric Acid SCHEMBL7224380 | 0.91 | ADORA2A (0.68) | ADORA2AADORA3ADORA2BADORA1 | |
| Hydrochloric Acid SCHEMBL7224383 | 0.91 | ADORA2A (0.68) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL5088980 | 0.89 | ADORA2A (0.59) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL5088973 | 0.89 | ADORA2A (0.59) | ADORA2AADORA3ADORA2BADORA1 | |
| Sulfuric Acid SCHEMBL7230588 | 0.89 | ADORA2A (0.67) | ADORA2AADORA3ADORA2BADORA1 | |
| Sulfuric Acid SCHEMBL7230587 | 0.89 | ADORA2A (0.67) | ADORA2AADORA3ADORA2BADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0948509-B1 | 2-(PURIN-9-YL)-TETRAHYDROFURAN-3,4-DIOL DERIVATIVES | GLAXO GROUP LTD (GB) | 2002-10-16 | — | — | EP | disclosed |