Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 20/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7525947 | 1.00 | TACR1 (0.74) | TACR1 | |
| SCHEMBL7525952 | 1.00 | TACR1 (0.74) | TACR1 | |
| SCHEMBL5297521 | 0.95 | TACR1 (0.76) | TACR1 | |
| SCHEMBL5297519 | 0.95 | TACR1 (0.76) | TACR1 | |
| SCHEMBL5297526 | 0.95 | TACR1 (0.76) | TACR1 | |
| SCHEMBL7518654 | 0.90 | TACR1 (0.82) | TACR1 | |
| SCHEMBL7518662 | 0.90 | TACR1 (0.82) | TACR1 | |
| SCHEMBL7518666 | 0.90 | TACR1 (0.82) | TACR1 | |
| SCHEMBL7521175 | 0.89 | TACR1 (0.59) | TACR1 | |
| SCHEMBL7521171 | 0.89 | TACR1 (0.59) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6479518-B2 | PSYCHOLOGICAL DISORDERS | MERCK & CO., INC. | 2002-11-12 | — | — | US | disclosed |
| US-20020042431-A1 | Zwitterionic tachykinin receptor antagonists | MERCK & CO., INC. | 2002-04-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020042431-A1 | Zwitterionic tachykinin receptor antagonists | NPY5R, NPY1R, NPY2R | TACR1 11/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.