SCHEMBL7526116

SCHEMBL7526116

COC(=O)c1ccc(NS(=O)(=O)C(F)(F)F)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 5/20 0.61
SMN1; SMN2 Q16637 2/20 0.61
MAPK1 P28482 2/20 0.61
PTPN1 P18031 1/20 0.57
PTPN11 Q06124 1/20 0.56
CA2 P00918 3/20 0.51
MAPT P10636 2/20 0.51
HTT P42858 2/20 0.51
ALDH1A1 P00352 1/20 0.51
GAA P10253 1/20 0.51
ALOX15 P16050 1/20 0.51
TSHR P16473 1/20 0.51
PTPRB P23467 1/20 0.50
MEN1 O00255 2/20 0.49
KMT2A Q03164 2/20 0.49
NPC1 O15118 2/20 0.49
RAB9A P51151 2/20 0.49
LMNA P02545 1/20 0.48
POLB P06746 1/20 0.47
ATM Q13315 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL691500 0.84 HPGD (0.68) HPGDSMN1; SMN2MAPK1PTPN1CA2
SCHEMBL6467240 0.83 KDM4E (0.50) HPGDSMN1; SMN2MAPK1PTPN1PTPN11
SCHEMBL4724618 0.83 SMN1; SMN2 (0.70) HPGDSMN1; SMN2MAPK1PTPN1PTPN11
SCHEMBL6522527 0.81 HPGD (0.67) HPGDSMN1; SMN2MAPK1CA2MAPT
SCHEMBL7279576 0.81 MAPK1 (0.62) SMN1; SMN2MAPK1PTPN1PTPN11CA2
SCHEMBL13719525 0.80 MAPK1 (0.61) SMN1; SMN2MAPK1PTPN1PTPN11CA2
SCHEMBL3378865 0.79 SMN1; SMN2 (0.60) SMN1; SMN2MAPK1PTPN1PTPN11CA2
SCHEMBL7433625 0.79 MAPK1 (0.60) SMN1; SMN2MAPK1PTPN1PTPN11CA2
SCHEMBL63833 0.79 HPGD (0.70) HPGDSMN1; SMN2CA2MAPTHTT
SCHEMBL6526759 0.79 HPGD (0.69) HPGDSMN1; SMN2CA2MAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230359119-A1 RESIST COMPOSITION AND PATTERN FORMING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-11-09 US disclosed
EP-0684517-B1 Photographic element with silver halide emulsion layer of low developability and having an associated high dye-yield coupler EASTMAN KODAK CO (US) 2002-07-24 EP disclosed
EP-0684514-B1 Tight-wrapped photographic element containing a high dye-yield coupler EASTMAN KODAK CO (US) 2002-07-17 EP disclosed
EP-0684516-B1 Photographic element containing a high dye-yield coupler with a methine dye chromophore EASTMAN KODAK CO (US) 2002-01-23 EP disclosed
EP-0684518-B1 Photographic element containing high dye-yield couplers having improved reactivity EASTMAN KODAK CO (US) 2001-07-18 EP disclosed
US-6007973-A Tight wrapped photographic element containing a high dye-yield coupler EASTMAN KODAK COMPANY (US) 1999-12-28 US disclosed
US-5998121-A HIGH DYE-YIELD COUPLER THAT RELEASES A DYE OR DYE PRECURSOR HAVING AN ELECTRICALLY NEUTRAL DYE CHROMOPHORE. EASTMAN KODAK COMPANY (US) 1999-12-07 US disclosed
EP-0684514-A1 Tight-wrapped photographic element containing a high dye-yield coupler EASTMAN KODAK COMPANY (US) 1995-11-29 EP disclosed
EP-0684516-A1 Photographic element containing a high dye-yield coupler with a methine dye chromophore EASTMAN KODAK COMPANY (US) 1995-11-29 EP disclosed
EP-0684517-A1 Photographic element with silver halide emulsion layer of low developability and having an associated high dye-yield coupler EASTMAN KODAK COMPANY (US) 1995-11-29 EP disclosed
EP-0684518-A1 Photographic element containing high dye-yield couplers having improved reactivity EASTMAN KODAK COMPANY (US) 1995-11-29 EP disclosed
US-5470688-A Heat development of elements containing methine-dye releasing couplers EASTMAN KODAK COMPANY (US) 1995-11-28 US disclosed
US-5457004-A Exposure the element, comprising a substrate and a photographic silver halide emulsion layer associated with high yield coupler, with oxidized color developer forming an image EASTMAN KODAK COMPANY (US) 1995-10-10 US disclosed
US-5455140-A Image quality, preferred hues EASTMAN KODAK COMPANY (US) 1995-10-03 US disclosed
US-5447819-A Photographic element containing high dye-yield couplers having improved reactivity EASTMAN KODAK COMPANY (US) 1995-09-05 US disclosed