Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Propylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7530093 | 0.81 | TDP1 (0.38) | TDP1 | |
| SCHEMBL31150 | 0.81 | TSHR (0.33) | — | |
| Ethylene Glycol SCHEMBL7523660 | 0.79 | TSHR (0.35) | — | |
| Ethylene Glycol SCHEMBL7524267 | 0.77 | TSHR (0.30) | — | |
| Ethylene Glycol SCHEMBL7524084 | 0.77 | TSHR (0.30) | — | |
| Ethylene Glycol SCHEMBL7521890 | 0.77 | TSHR (0.33) | — | |
| SCHEMBL7526141 | 0.74 | TSHR (0.38) | — | |
| Propylene Glycol SCHEMBL27443040 | 0.73 | — | — | |
| Propylene Glycol SCHEMBL1834314 | 0.71 | TDP1 (0.46) | TDP1 | |
| Propylene Glycol SCHEMBL5558430 | 0.71 | TDP1 (0.59) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0637761-B1 | Process for the production of water-absorptive contact lens | MENICON CO LTD (JP) | 2002-03-13 | — | — | EP | disclosed |
| EP-0589430-B1 | Water-absorptive contact lens | MENICON CO LTD (JP) | 1999-06-16 | — | — | EP | disclosed |
| US-5502086-A | CROSSLINKED POLYMER OF ACRYLATE AND VINYL ESTER | MENICON CO., LTD. (JP) | 1996-03-26 | — | — | US | disclosed |
| US-5426133-A | Crosslinked, saponified acrylic copolymers; dimensional and storage stability, heat resistance | MENICON CO., LTD. (JP) | 1995-06-20 | — | — | US | disclosed |
| EP-0637761-A1 | Water-absorptive contact lens and process for its production | Menicon Co., Ltd. (JP) | 1995-02-08 | — | — | EP | disclosed |
| EP-0332179-B1 | Highly water-absorptive ocular lens material | MENICON CO LTD (JP) | 1994-09-14 | — | — | EP | disclosed |
| EP-0589430-A2 | Water-absorptive contact lens | Menicon Co., Ltd. (JP) | 1994-03-30 | — | — | EP | disclosed |
| US-4920180-A | Hydrophilic polymer | MENICON CO., LTD. (JP) | 1990-04-24 | — | — | US | disclosed |
| EP-0332179-A2 | Highly water-absorptive ocular lens material | Menicon Co., Ltd. (JP) | 1989-09-13 | — | — | EP | disclosed |