Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | UGCG | Q16739 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL7526322 | 0.82 | EPHX2 (0.40) | TLR2EPHX2HTTALDH1A1MEN1 | |
| Maleic Acid SCHEMBL7526315 | 0.82 | EPHX2 (0.40) | TLR2EPHX2HTTALDH1A1MEN1 | |
| SCHEMBL18751407 | 0.73 | MEN1 (0.37) | EPHX2ALDH1A1MEN1KMT2ATP53 | |
| SCHEMBL17948069 | 0.72 | KMT2A (0.43) | ALDH1A1MEN1KMT2ACYP3A4CYP2C19 | |
| SCHEMBL17955772 | 0.72 | MEN1 (0.43) | ALDH1A1MEN1KMT2ACYP3A4CYP2D6 | |
| SCHEMBL17955787 | 0.72 | MEN1 (0.43) | ALDH1A1MEN1KMT2ACYP3A4CYP2D6 | |
| SCHEMBL17955616 | 0.72 | MEN1 (0.43) | ALDH1A1MEN1KMT2ACYP3A4CYP2D6 | |
| SCHEMBL3071012 | 0.71 | KDM4E (0.48) | EPHX2ALDH1A1EPHX1 | |
| SCHEMBL7533440 | 0.71 | KDM4E (0.48) | EPHX2ALDH1A1EPHX1 | |
| SCHEMBL3064740 | 0.71 | KDM4E (0.48) | EPHX2ALDH1A1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832079-B1 | ANTI-ISCHAEMIC HYDROXYLAMINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS | BIOREX KUTATO FEJLESZTOE KFT (HU) | 2002-03-27 | — | — | EP | disclosed |
| US-6002002-A | Anti-ischaemic hydroxylamine derivatives and pharmaceutical compositions | BIOREX RESEARCH & DEVELOPMENT CO. (HU) | 1999-12-14 | — | — | US | disclosed |
| EP-0832079-A1 | ANTI-ISCHAEMIC HYDROXYLAMINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS | BIOREX KUTATO ES FEJLESZTÖ RT. (HU) | 1998-04-01 | — | — | EP | disclosed |
| WO-1997000251-A1 | ANTI-ISCHAEMIC HYDROXYLAMINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS | BIOREX KUTATO ES FEJLESZTO RT. (HU) | 1997-01-03 | — | — | WO | disclosed |