Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 5/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7521892 | 1.00 | MEN1 (0.46) | MEN1KMT2ATSHRMAPK1ALDH1A1 | |
| SCHEMBL7525922 | 1.00 | MEN1 (0.46) | MEN1KMT2ATSHRMAPK1ALDH1A1 | |
| SCHEMBL7523664 | 0.87 | — | — | |
| Triethylene Glycol SCHEMBL7526326 | 0.85 | MEN1 (0.48) | MEN1KMT2ATSHRMAPK1ALDH1A1 | |
| Tetraethylene Glycol SCHEMBL7525918 | 0.85 | MEN1 (0.48) | MEN1KMT2ATSHRMAPK1ALDH1A1 | |
| SCHEMBL7519201 | 0.80 | GAA (0.33) | MEN1KMT2ATSHRALDH1A1THRB | |
| SCHEMBL7524537 | 0.80 | GAA (0.33) | MEN1KMT2ATSHRALDH1A1THRB | |
| SCHEMBL29450507 | 0.78 | MEN1 (0.55) | MEN1KMT2ATSHRMAPK1ALDH1A1 | |
| SCHEMBL10619745 | 0.78 | TSHR (0.47) | MEN1KMT2ATSHRMAPK1ALDH1A1 | |
| SCHEMBL231580 | 0.77 | TSHR (0.42) | MEN1KMT2ATSHRMAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0637761-B1 | Process for the production of water-absorptive contact lens | MENICON CO LTD (JP) | 2002-03-13 | — | — | EP | disclosed |
| EP-0589430-B1 | Water-absorptive contact lens | MENICON CO LTD (JP) | 1999-06-16 | — | — | EP | disclosed |
| US-5502086-A | CROSSLINKED POLYMER OF ACRYLATE AND VINYL ESTER | MENICON CO., LTD. (JP) | 1996-03-26 | — | — | US | disclosed |
| US-5426133-A | Crosslinked, saponified acrylic copolymers; dimensional and storage stability, heat resistance | MENICON CO., LTD. (JP) | 1995-06-20 | — | — | US | disclosed |
| EP-0637761-A1 | Water-absorptive contact lens and process for its production | Menicon Co., Ltd. (JP) | 1995-02-08 | — | — | EP | disclosed |
| EP-0332179-B1 | Highly water-absorptive ocular lens material | MENICON CO LTD (JP) | 1994-09-14 | — | — | EP | disclosed |
| EP-0589430-A2 | Water-absorptive contact lens | Menicon Co., Ltd. (JP) | 1994-03-30 | — | — | EP | disclosed |
| US-4920180-A | Hydrophilic polymer | MENICON CO., LTD. (JP) | 1990-04-24 | — | — | US | disclosed |
| EP-0332179-A2 | Highly water-absorptive ocular lens material | Menicon Co., Ltd. (JP) | 1989-09-13 | — | — | EP | disclosed |