Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 5/20 | 0.43 |
| ▸ | PTGDR | Q13258 | 3/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 7/20 | 0.42 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 4/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7524434 | 0.93 | TP53 (0.41) | PTGIRPTGDRPTGDR2PLA2G1BHTT | |
| SCHEMBL7555841 | 0.90 | PTGIR (0.43) | PTGIRPTGDRPTGDR2PPARDFFAR1 | |
| SCHEMBL7522034 | 0.90 | PTGIR (0.43) | PTGIRPTGDRPTGDR2PPARDFFAR1 | |
| SCHEMBL7527946 | 0.89 | PPARD (0.39) | PTGIRPTGDRPTGDR2PPARDFFAR1 | |
| SCHEMBL7523254 | 0.88 | RXFP1 (0.40) | PTGIRPTGDRPTGDR2PPARDFFAR1 | |
| SCHEMBL7523182 | 0.88 | PTGDR2 (0.41) | PTGIRPTGDRPTGDR2PPARDFFAR1 | |
| SCHEMBL7518610 | 0.87 | PTGIR (0.41) | PTGIRPTGDRPTGDR2HTTL3MBTL1 | |
| SCHEMBL7520993 | 0.86 | PTGDR2 (0.43) | PTGIRPTGDRPTGDR2PPARD | |
| SCHEMBL7523911 | 0.85 | PTGIR (0.39) | PTGIRPTGDRPPARDFFAR1PPARA | |
| SCHEMBL7517343 | 0.85 | PTGDR2 (0.42) | PTGDR2PPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6417213-B2 | ANTICOAGULANTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-07-09 | — | — | US | disclosed |
| US-20020006944-A1 | Tricyclic compounds, their production and use | OHKAWA SHIGENORI (JP) | 2002-01-17 | — | — | US | disclosed |
| US-6248766-B1 | CARDIOVASCULAR DISORDERS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-06-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020006944-A1 | Tricyclic compounds, their production and use | CNR1, PTGER1, PTGDR | PTGIR 11/4885PTGDR 3/4885PTGDR2 10/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.