Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | MAOB | P27338 | 6/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | EDNRB | P24530 | 1/20 | 0.40 |
| ▸ | EDNRA | P25101 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7524792 | 0.81 | KMT2A (0.49) | KMT2ATDP1L3MBTL1MAOBFAAH | |
| SCHEMBL11663617 | 0.75 | MAOB (0.68) | KMT2ATDP1L3MBTL1MAOBFAAH | |
| SCHEMBL11698521 | 0.74 | MAOB (0.71) | KMT2ATDP1L3MBTL1MAOBCYP3A4 | |
| SCHEMBL1299344 | 0.73 | KMT2A (1.00) | KMT2ATDP1L3MBTL1MAOBCYP3A4 | |
| SCHEMBL1155269 | 0.72 | KMT2A (0.62) | KMT2ATDP1L3MBTL1MAOBCYP3A4 | |
| SCHEMBL8035300 | 0.71 | VKORC1 (0.41) | TDP1HPGDSMN1; SMN2 | |
| SCHEMBL5798301 | 0.71 | VKORC1 (0.41) | KDM4EEDNRBEDNRAHPGD | |
| SCHEMBL11613149 | 0.70 | MAOB (0.73) | KMT2ATDP1L3MBTL1MAOBMAOA | |
| SCHEMBL11559934 | 0.70 | MAOB (0.68) | KMT2ATDP1L3MBTL1MAOBCYP3A4 | |
| SCHEMBL3220077 | 0.69 | NPC1 (0.56) | KMT2ATDP1L3MBTL1MAOBCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1244617-A1 | SUBSTITUTED AMINOALKYLAMIDE DERIVATIVES AS ANTAGONISTS OF FOLLICLE STIMULATING HORMONE | Ortho-McNeil Pharmaceutical, Inc. (US) | 2002-10-02 | — | — | EP | claimed |
| WO-2001047875-A1 | SUBSTITUTED AMINOALKYLAMIDE DERIVATIVES AS ANTAGONISTS OF FOLLICLE STIMULATING HORMONE | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2001-07-05 | — | — | WO | claimed |