⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11648751 | 0.84 | — | — | |
| SCHEMBL29085523 | 0.82 | — | — | |
| SCHEMBL833026 | 0.79 | — | — | |
| SCHEMBL27552724 | 0.79 | — | — | |
| SCHEMBL3818439 | 0.77 | — | — | |
| SCHEMBL30324581 | 0.74 | — | — | |
| SCHEMBL27589557 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL28576918 | 0.69 | — | — | |
| SCHEMBL2551319 | 0.59 | — | — | |
| SCHEMBL5931153 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0900781-B1 | Phenolic acid amides of hydroxy substituted benzylamines | HAARMANN & REIMER GMBH (DE) | 2002-03-20 | — | — | EP | claimed |
| US-6117365-A | N-(3,4-DIHYDROXYBENZYL)-3,5-DIMETHOXY-4-HYDROXY-E-CINNAMIDE, FOR EXAMPLE; USE AS ANTIOXIDANTS OR AS FREE-RADICAL SCAVENGERS, IN PARTICULAR IN THE COSMETIC OR DERMATOLOGICAL FIELDS, AND IN FOODS | HAARMANN & REIMER GMBH (DE) | 2000-09-12 | — | — | US | claimed |
| EP-0900781-A2 | Phenolic acid amides of hydroxy substituted benzylamines | HAARMANN & REIMER GMBH (DE) | 1999-03-10 | — | — | EP | claimed |
| EP-0900781-B1 | Phenolic acid amides of hydroxy substituted benzylamines | HAARMANN & REIMER GMBH (DE) | 2002-03-20 | — | — | EP | disclosed |
| US-6117365-A | N-(3,4-DIHYDROXYBENZYL)-3,5-DIMETHOXY-4-HYDROXY-E-CINNAMIDE, FOR EXAMPLE; USE AS ANTIOXIDANTS OR AS FREE-RADICAL SCAVENGERS, IN PARTICULAR IN THE COSMETIC OR DERMATOLOGICAL FIELDS, AND IN FOODS | HAARMANN & REIMER GMBH (DE) | 2000-09-12 | — | — | US | disclosed |
| EP-0900781-A2 | Phenolic acid amides of hydroxy substituted benzylamines | HAARMANN & REIMER GMBH (DE) | 1999-03-10 | — | — | EP | disclosed |