SCHEMBL7527221

SCHEMBL7527221

O=C1OC(CNC(=S)N2CCC2)CN1c1cccc(F)c1N1CCSCC1

nearest known ligand 0.51

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MAOB P27338 4/20 0.51
MAOA P21397 3/20 0.51
F10 P00742 14/20 0.49
LMNA P02545 1/20 0.40
PTGS1 P23219 1/20 0.40
CALML3 P27482 1/20 0.40
SDHA P31040 1/20 0.40
GRM2 Q14416 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7527213 1.00 MAOB (0.51) MAOBMAOAF10LMNAPTGS1
SCHEMBL7953617 0.90 MAOB (0.58) MAOBMAOAF10LMNAPTGS1
SCHEMBL7675015 0.87 F10 (0.50) MAOBMAOAF10LMNAPTGS1
SCHEMBL7675024 0.87 F10 (0.50) MAOBMAOAF10LMNAPTGS1
SCHEMBL7530454 0.85 MAOB (0.51) MAOBMAOAF10LMNAPTGS1
SCHEMBL7530462 0.85 MAOB (0.51) MAOBMAOAF10LMNAPTGS1
SCHEMBL6040534 0.83 MAOB (0.75) MAOBMAOAF10LMNAPTGS1
SCHEMBL6040527 0.83 MAOB (0.75) MAOBMAOAF10LMNAPTGS1
SCHEMBL7158483 0.82 MAOB (0.56) MAOBMAOAF10LMNAPTGS1
SCHEMBL7158485 0.82 MAOB (0.56) MAOBMAOAF10LMNAPTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020016323-A1 Oxazolidinone antibacterial agents having a thiocarbonyl functionality PHARMACIA & UPJOHN COMPANY 2002-02-07 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020016323-A1 Oxazolidinone antibacterial agents having a thiocarbonyl functionality OXA1L, MRPL21, TOP1 MAOB 2998/4885MAOA 3306/4885F10 3383/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.