Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | BCL3 | P20749 | 3/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.58 |
| ▸ | PARP1 | P09874 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7526242 | 0.92 | POLB (0.66) | KMT2AALDH1A1BCL3HPGD | |
| SCHEMBL21347706 | 0.86 | KMT2A (0.66) | KMT2AMEN1ALDH1A1BCL3HPGD | |
| SCHEMBL31298077 | 0.85 | KMT2A (0.67) | KMT2AMEN1ALDH1A1BCL3HPGD | |
| SCHEMBL13164059 | 0.84 | MEN1 (0.66) | KMT2AMEN1ALDH1A1BCL3HPGD | |
| SCHEMBL8161181 | 0.84 | BCL3 (0.84) | KMT2AMEN1ALDH1A1BCL3HPGD | |
| SCHEMBL8167729 | 0.84 | KMT2A (0.66) | KMT2AMEN1ALDH1A1BCL3HPGD | |
| SCHEMBL24062684 | 0.83 | KMT2A (0.62) | KMT2AMEN1ALDH1A1BCL3HPGD | |
| SCHEMBL10352662 | 0.83 | KMT2A (0.65) | KMT2AMEN1ALDH1A1BCL3HPGD | |
| SCHEMBL8378435 | 0.83 | KMT2A (0.65) | KMT2AMEN1ALDH1A1BCL3HPGD | |
| SCHEMBL5795351 | 0.82 | KMT2A (0.63) | KMT2AMEN1ALDH1A1BCL3HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002020437-A2 | BASIC COMPOUNDS CONTAINING TERTIARY AMIDES WITH ACTIVITY ON TACHYKININ RECEPTORS, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | MENARINI RICERCHE S.P.A. (IT) | 2002-03-14 | — | — | WO | disclosed |