Chlorobenzene

Chlorobenzene

SCHEMBL7528039

C1CCC2CCCCC2C1.Clc1ccccc1

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.58
ALDH1A1 P00352 5/20 0.42
CYP1A2 P05177 1/20 0.42
SMN1; SMN2 Q16637 2/20 0.39
MAPT P10636 2/20 0.39
HPGD P15428 2/20 0.39
KDM4E B2RXH2 1/20 0.39
GAA P10253 2/20 0.38
LMNA P02545 1/20 0.38
PSEN1 P49768 1/20 0.38
PSEN2 P49810 1/20 0.38
APH1B Q8WW43 1/20 0.38
NCSTN Q92542 1/20 0.38
APH1A Q96BI3 1/20 0.38
PSENEN Q9NZ42 1/20 0.38
SLC6A2 P23975 1/20 0.37
SLC6A4 P31645 1/20 0.37
SLC6A3 Q01959 1/20 0.37
AGER Q15109 1/20 0.37
POLB P06746 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Chlorobenzene SCHEMBL28829691 0.89 TSHR (0.65) TSHRALDH1A1CYP1A2LMNAPSEN1
Chlorobenzene SCHEMBL7534942 0.80 TSHR (0.52) TSHRALDH1A1CYP1A2SMN1; SMN2HPGD
Chlorobenzene SCHEMBL28562804 0.80 TSHR (0.52) TSHRALDH1A1CYP1A2SMN1; SMN2KDM4E
Chlorobenzene SCHEMBL7318139 0.80 TSHR (0.79) TSHRALDH1A1CYP1A2KDM4EGAA
Chlorobenzene SCHEMBL21313673 0.78 TSHR (0.50) TSHRALDH1A1CYP1A2SMN1; SMN2MAPT
Chlorobenzene SCHEMBL1275085 0.78 TSHR (0.50) TSHRCYP1A2LMNAAGER
Chlorobenzene SCHEMBL28544679 0.77 TSHR (0.55) TSHRALDH1A1CYP1A2SMN1; SMN2KDM4E
SCHEMBL24715429 0.76 TSHR (1.00) TSHRALDH1A1CYP1A2KDM4EGAA
Chlorobenzene SCHEMBL1568605 0.76 TSHR (1.00) TSHRALDH1A1CYP1A2KDM4EGAA
Chlorobenzene SCHEMBL2044 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109982999-A The imidazolyl methyl-derivatives that new 5- replaces 拜耳作物科学股份公司 2019-07-05 CN disclosed
CN-109803965-A The imidazolyl methyl dioxolane derivatives that 5- as fungicide replaces 拜耳作物科学股份公司 2019-05-24 CN disclosed
CN-105636947-B N- heteroaryl (thio) carbonyl -2- (Benzocycloalkene -1- base) cyclammonium and its purposes as fungicide 拜耳作物科学股份公司 2019-05-07 CN disclosed
CN-109476606-A Benzosultams and analogs and their use as fungicides 拜耳作物科学股份公司 2019-03-15 CN disclosed
CN-105873907-B N-cycloalkyl-N- { [2- (1-substituted cycloalkyl) phenyl ] methylene } - (thio) carboxamide derivatives 拜耳作物科学股份公司 2019-03-12 CN disclosed
CN-105722393-B N- naphthenic base-N- (double heterocycle methylenes)-(thio) carboxamides derivatives 拜耳作物科学股份公司 2018-11-20 CN disclosed
CN-105636939-B N- naphthenic base-N- [(two ring group phenyl) methylene]-(thio) carboxamides derivatives 拜耳作物科学股份公司 2018-08-31 CN disclosed
CN-105339353-B N- naphthenic base-N- [(fused phenyl) methylene]-(thio) carboxamides derivatives 拜耳作物科学股份公司 2018-08-10 CN disclosed
CN-108349897-A Trisubstituted silylphenoxyheterocycles and analogs 拜耳作物科学股份公司 2018-07-31 CN disclosed
CN-104812751-B Nitrogen-containing heterocyclic compounds for the control of plant diseases 拜尔农作物科学股份公司 2018-06-05 CN disclosed
CN-104220425-B N-cycloalkyl-N-[(cycloalkenyl group phenyl) methylene]-(sulfur generation) carboxamide derivative 拜耳知识产权有限责任公司 2016-10-19 CN disclosed
CN-104039769-B 3-[(1,3-thiazole-4-yl methoxyimino) (phenyl) methyl]-2-substituted-1,2,4-diazole-5 (2H) the-one derivant of antifungal 拜耳知识产权有限责任公司 2016-10-19 CN disclosed
CN-105873907-A N-cycloalkyl-N- { [2- (1-substituted cycloalkyl) phenyl ] methylene } - (thio) carboxamide derivatives 拜耳作物科学股份公司 2016-08-17 CN disclosed
CN-105793243-A N-cycloalkyl-N- { [2- (1-substituted cycloalkyl) phenyl ] methylene } - (thio) carboxamide derivatives 拜耳作物科学股份公司 2016-07-20 CN disclosed
CN-105722393-A N-cycloalkyl-N-(biheterocyclymethylene)-(thio)carboxamide derivatives 拜耳作物科学股份公司 2016-06-29 CN disclosed
CN-105705490-A Fungicidal 3-{phenyl[(heterocyclylmethoxy)imino]methyl}-heterocycle derivatives 拜耳作物科学股份公司 2016-06-22 CN disclosed
CN-102007120-A Fungicide hydroxyimino-heterocyclic derivatives BAYER CROPSCIENCE AG 2011-04-06 CN disclosed
CN-101970423-A Fungicide hydroximoyl-tetrazole derivatives BAYER CROPSCIENCE AG 2011-02-09 CN disclosed
CN-101687839-A Fungicide phenyl-pyrimidinyl-amino derivatives BAYER CROPSCIENCE SA 2010-03-31 CN disclosed
US-20020072524-A1 Aryl fused azapolycyclic compounds WADSWORTH JOTHAM (US) 2002-06-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020072524-A1 Aryl fused azapolycyclic compounds GRIN2C, GRIN2A, GRIN2B TSHR 1411/4885ALDH1A1 260/4885CYP1A2 12/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.