SCHEMBL7528165

SCHEMBL7528165

CC(=O)CC(=O)Nc1ccc(Cl)cc1C(=O)O

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.71
HSD17B10 Q99714 1/20 0.71
MEN1 O00255 4/20 0.58
KMT2A Q03164 4/20 0.58
ALDH1A1 P00352 3/20 0.58
SMN1; SMN2 Q16637 2/20 0.57
GAA P10253 1/20 0.57
SERPINE1 P05121 4/20 0.55
AKR1C3 P42330 2/20 0.52
AKR1C2 P52895 2/20 0.52
AKR1C4 P17516 1/20 0.52
AKR1C1 Q04828 1/20 0.52
POLB P06746 3/20 0.52
G6PD P11413 1/20 0.52
PPARG P37231 1/20 0.51
PPARA Q07869 1/20 0.51
GABRP O00591 1/20 0.50
GABRD O14764 1/20 0.50
GABRA1 P14867 1/20 0.50
GABRB1 P18505 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7080579 0.88 MEN1 (0.75) KDM4EHSD17B10MEN1KMT2AALDH1A1
SCHEMBL6510154 0.85 KMT2A (0.63) KDM4EHSD17B10MEN1KMT2AALDH1A1
SCHEMBL30044907 0.85 KMT2A (0.63) KDM4EHSD17B10MEN1KMT2AALDH1A1
SCHEMBL13263480 0.84 SMN1; SMN2 (0.71) KDM4EMEN1KMT2AALDH1A1SMN1; SMN2
SCHEMBL27331760 0.84 KDM4E (0.66) KDM4EHSD17B10MEN1KMT2AALDH1A1
SCHEMBL418999 0.84 KDM4E (0.66) KDM4EHSD17B10MEN1KMT2AALDH1A1
SCHEMBL7045036 0.83 KDM4E (1.00) KDM4EHSD17B10MEN1KMT2AALDH1A1
SCHEMBL8482804 0.83 KDM4E (0.64) KDM4EHSD17B10MEN1KMT2AALDH1A1
SCHEMBL9180503 0.82 HPGD (0.68) KDM4EMEN1KMT2AALDH1A1SMN1; SMN2
SCHEMBL31590796 0.82 HPGD (0.68) KDM4EMEN1KMT2AALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1134517-C Disazo pigment composition and printing ink 3M 2004-01-14 CN disclosed
EP-0823459-B1 Disazo pigment composition and printing ink DAINIPPON INK & CHEMICALS (JP) 2002-04-17 EP disclosed
US-5803962-A Disazo pigment composition and printing ink DAINIPPON INK AND CHEMICALS, INC. (JP) 1998-09-08 US disclosed
CN-1175607-A Tetrazo pigment composition and printing ink DAINIPPON INK & CHEMICALS (JP) 1998-03-11 CN disclosed
EP-0823459-A2 Disazo pigment composition and printing ink DAINIPPON INK AND CHEMICALS, INC. (JP) 1998-02-11 EP disclosed