Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 2/20 | 0.51 |
| ▸ | RARB | P10826 | 8/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | RARA | P10276 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | MTOR | P42345 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | THRA | P10827 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7601727 | 0.89 | RARB (0.61) | S1PR1RARBMEN1ALDH1A1RARA | |
| SCHEMBL7560399 | 0.84 | MAPT (0.48) | S1PR1RARBMEN1ALDH1A1RARA | |
| SCHEMBL7561410 | 0.84 | MAPT (0.48) | S1PR1RARBMEN1ALDH1A1RARA | |
| SCHEMBL7521960 | 0.82 | S1PR1 (0.50) | S1PR1RARBMEN1ALDH1A1RARA | |
| SCHEMBL7468384 | 0.81 | RARB (0.51) | S1PR1RARBMEN1ALDH1A1RARA | |
| SCHEMBL7467122 | 0.79 | MAOB (0.52) | S1PR1MAOBACHE | |
| SCHEMBL4929717 | 0.78 | RARB (0.73) | RARBMEN1ALDH1A1RARAMAPT | |
| SCHEMBL14832681 | 0.77 | MAOB (0.53) | S1PR1MEN1ALDH1A1KMT2AMAOA | |
| SCHEMBL29873244 | 0.77 | MAOB (0.53) | S1PR1MEN1ALDH1A1KMT2AMAOA | |
| SCHEMBL2241887 | 0.77 | RARB (0.73) | RARBMEN1ALDH1A1RARAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1214306-A1 | LIQUID CRYSTAL COMPOUNDS | Qinetiq Limited (GB) | 2002-06-19 | — | — | EP | disclosed |
| WO-2001021606-A1 | LIQUID CRYSTAL COMPOUNDS | QINETIQ LIMITED (GB) | 2001-03-29 | — | — | WO | disclosed |