Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7344790 | 0.98 | GLA (0.55) | GLAITGB3ITGA2BSMN1; SMN2CYP1A2 | |
| SCHEMBL905223 | 0.98 | GLA (0.55) | GLAITGB3ITGA2BSMN1; SMN2CYP1A2 | |
| SCHEMBL8795424 | 0.96 | GLA (0.53) | GLAITGB3ITGA2BSMN1; SMN2CYP1A2 | |
| Hydrochloric Acid SCHEMBL28282429 | 0.96 | GLA (0.59) | GLAITGB3ITGA2BSMN1; SMN2CYP1A2 | |
| SCHEMBL7508214 | 0.96 | GLA (0.53) | GLAITGB3ITGA2BSMN1; SMN2CYP1A2 | |
| Aziridine SCHEMBL28507214 | 0.96 | GLA (0.57) | GLAITGB3ITGA2BSMN1; SMN2CYP1A2 | |
| SCHEMBL9059317 | 0.91 | CXCR4 (0.52) | GLAITGB3ITGA2BSMN1; SMN2CYP1A2 | |
| SCHEMBL3193772 | 0.91 | GLA (0.46) | GLAITGB3ITGA2BSMN1; SMN2CYP1A2 | |
| SCHEMBL9937405 | 0.88 | SMN1; SMN2 (0.62) | GLAITGB3ITGA2BSMN1; SMN2CYP1A2 | |
| SCHEMBL6371114 | 0.87 | CXCR4 (0.61) | GLAITGB3ITGA2BSMN1; SMN2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1051257-B1 | METHOD FOR PREPARING POLYAZACYCLOALKANES GRAFTED ON SILICA GEL AND USE OF GRAFTED COMPOUNDS | AIR LIQUIDE (FR) | 2002-04-03 | — | — | EP | claimed |
| WO-1996011189-A1 | POLYAZACYCLOALKANE DERIVATIVES, THEIR METAL COMPLEXES AND PHARMACEUTICAL PRODUCTS INCORPORATING THESE COMPLEXES | L'AIR LIQUIDE SOCIETE ANONYME POUR L'ETUDE ET L'EXPLOITATION DES PROCEDES GEORGES CLAUDE (FR) | 1996-04-18 | — | — | WO | claimed |