Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 8/20 | 0.67 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.56 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.55 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.54 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.54 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.54 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19493363 | 1.00 | TYMP (0.67) | TYMPP2RY12ADORA1P2RY2P2RY1 | |
| SCHEMBL17304362 | 1.00 | TYMP (0.67) | TYMPP2RY12ADORA1P2RY2P2RY1 | |
| SCHEMBL917680 | 1.00 | TYMP (0.67) | TYMPP2RY12ADORA1P2RY2P2RY1 | |
| SCHEMBL917678 | 1.00 | TYMP (0.67) | TYMPP2RY12ADORA1P2RY2P2RY1 | |
| SCHEMBL19493362 | 1.00 | TYMP (0.67) | TYMPP2RY12ADORA1P2RY2P2RY1 | |
| SCHEMBL29679722 | 1.00 | TYMP (0.67) | TYMPP2RY12ADORA1P2RY2P2RY1 | |
| SCHEMBL8386141 | 1.00 | TYMP (0.67) | TYMPP2RY12ADORA1P2RY2P2RY1 | |
| SCHEMBL7529826 | 0.99 | TYMP (0.66) | TYMPP2RY12ADORA1P2RY2P2RY1 | |
| SCHEMBL9024707 | 0.94 | TYMP (0.69) | TYMPP2RY12ADORA1P2RY2P2RY1 | |
| SCHEMBL9550751 | 0.94 | TYMP (0.69) | TYMPP2RY12ADORA1P2RY2P2RY1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1186306-A1 | Labeled nucleosides and method for their preparation | K.U. Leuven Research & Development (BE) | 2002-03-13 | — | — | EP | disclosed |
| EP-0694559-B1 | 2',5'-Phosphorothioate oligoadenylates and antiviral uses thereof | UNIV TEMPLE (US) | 1999-04-14 | — | — | EP | disclosed |
| US-5556840-A | 2',5'-phosphorothioate oligoadenylates as anitiviral agents | TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 1996-09-17 | — | — | US | disclosed |
| EP-0389521-B1 | 2',5'-PHOSPHOROTHIOATE OLIGOADENYLATES AND ANTIVIRAL USES THEREOF | UNIV TEMPLE (US) | 1996-03-20 | — | — | EP | disclosed |
| EP-0694559-A2 | 2',5'-Phosphorothioate oligoadenylates and antiviral uses thereof | Temple University of the Commonwealth System of Higher Education (US) | 1996-01-31 | — | — | EP | disclosed |
| US-5405939-A | viricides | TEMPLE UNIVERSITY OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 1995-04-11 | — | — | US | disclosed |
| US-5188897-A | Viricides, metabolic stability | TEMPLE UNIVERSITY OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 1993-02-23 | — | — | US | disclosed |
| EP-0389521-A4 | 2',5'-PHOSPHOROTHIOATE OLIGOADENYLATES AND ANTIVIRAL USES THEREOF | — | 1992-02-05 | — | — | EP | disclosed |
| EP-0389521-A1 | 2',5'-PHOSPHOROTHIOATE OLIGOADENYLATES AND ANTIVIRAL USES THEREOF | Temple University of the Commonwealth System of Higher Education (US) | 1990-10-03 | — | — | EP | disclosed |
| US-4924624-A | TOBACCO MOSAIC VIRUS | TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 1990-05-15 | — | — | US | disclosed |
| WO-1989003683-A1 | 2',5'-PHOSPHOROTHIOATE OLIGOADENYLATES AND ANTIVIRAL USES THEREOF | TEMPLE UNIVERSITY OF THE COMMONWEALTH SYSTEM OF HI (US) | 1989-05-05 | — | — | WO | disclosed |