Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5869121 | 0.84 | CYP3A4 (1.00) | CYP3A4 | |
| SCHEMBL5869210 | 0.78 | CYP3A4 (0.88) | CYP3A4 | |
| SCHEMBL5869116 | 0.76 | CYP3A4 (0.84) | CYP3A4 | |
| SCHEMBL5869097 | 0.76 | CYP3A4 (0.84) | CYP3A4 | |
| SCHEMBL7140734 | 0.73 | CYP3A4 (0.79) | CYP3A4 | |
| SCHEMBL5869013 | 0.72 | CYP3A4 (0.79) | CYP3A4 | |
| SCHEMBL5868761 | 0.72 | CYP3A4 (0.78) | CYP3A4 | |
| SCHEMBL6167087 | 0.70 | CYP3A4 (0.73) | CYP3A4 | |
| SCHEMBL5868980 | 0.69 | CYP3A4 (0.71) | CYP3A4 | |
| SCHEMBL5869173 | 0.69 | CYP3A4 (0.80) | CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1224175-A2 | BENZODIAZEPINE DERIVATIVES AS METABOTROPIC GLUTAMATE RECEPTOR ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2002-07-24 | — | — | EP | disclosed |
| WO-2001029012-A2 | BENZODIAZEPINE DERIVATIVES AS METABOTROPIC GLUTAMATE RECEPTOR ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2001-04-26 | — | — | WO | disclosed |