Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY1 | P47900 | 7/20 | 0.93 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.93 |
| ▸ | P2RX1 | P51575 | 3/20 | 0.93 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.93 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.93 |
| ▸ | SRC | P12931 | 2/20 | 0.93 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.93 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.93 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.93 |
| ▸ | TRPM2 | O94759 | 2/20 | 0.86 |
| ▸ | MACROD2 | A1Z1Q3 | 1/20 | 0.86 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.86 |
| ▸ | MACROD1 | Q9BQ69 | 1/20 | 0.86 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.79 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.79 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.79 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.79 |
| ▸ | LDHA | P00338 | 1/20 | 0.79 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.79 |
| ▸ | FBP1 | P09467 | 1/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Atpgammas SCHEMBL15082690 | 1.00 | P2RY1 (0.93) | P2RY1P2RY2P2RX1P2RX3ALDH1A1 | |
| Atpgammas SCHEMBL13996417 | 1.00 | P2RY1 (0.93) | P2RY1P2RY2P2RX1P2RX3ALDH1A1 | |
| Atpgammas SCHEMBL20164791 | 1.00 | P2RY1 (0.93) | P2RY1P2RY2P2RX1P2RX3ALDH1A1 | |
| SCHEMBL5269250 | 0.99 | P2RY1 (0.91) | P2RY1P2RY2P2RX1P2RX3ALDH1A1 | |
| SCHEMBL29141612 | 0.99 | P2RY1 (0.91) | P2RY1P2RY2P2RX1P2RX3ALDH1A1 | |
| SCHEMBL4357990 | 0.96 | P2RY1 (1.00) | P2RY1P2RY2P2RX1P2RX3ALDH1A1 | |
| SCHEMBL6516963 | 0.96 | P2RY1 (1.00) | P2RY1P2RY2P2RX1P2RX3ALDH1A1 | |
| SCHEMBL21067711 | 0.96 | P2RY1 (1.00) | P2RY1P2RY2P2RX1P2RX3ALDH1A1 | |
| Diadenosine Tetraphosphate SCHEMBL4363130 | 0.96 | P2RY1 (1.00) | P2RY1P2RY2P2RX1P2RX3ALDH1A1 | |
| Diadenosine Tetraphosphate SCHEMBL4069414 | 0.96 | P2RY1 (1.00) | P2RY1P2RY2P2RX1P2RX3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7960131-B2 | Functional genomic pore assay for mixed cell populations | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2011-06-14 | — | — | US | claimed |
| US-7560243-B2 | White blood cell functional assay | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2009-07-14 | — | — | US | claimed |
| US-20090053204-A1 | Functional Genomic Pore Assay For Mixed Cell Populations | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2009-02-26 | — | — | US | claimed |
| US-20040253650-A1 | White blood cell functional assay | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2004-12-16 | — | — | US | claimed |
| EP-3352794-B1 | COMBINATION OF A PROTEIN KINASE CK2 INHIBITOR AND AN ATAXIA TELANGIECTASIA MUTATED (ATM) KINASE INHIBITOR FOR TREATING RENAL CELL CARCINOMA | COMMISSARIAT ENERGIE ATOMIQUE (FR) | 2020-10-14 | — | — | EP | disclosed |
| EP-3684378-A2 | GAPMERS AND METHODS OF USING THE SAME FOR TREATMENT OF MUSCULAR DYSTROPHY | Children's National Medical Center (US) | 2020-07-29 | — | — | EP | disclosed |
| WO-2019147743-A1 | STRUCTURE-GUIDED CHEMICAL MODIFICATION OF GUIDE RNA AND ITS APPLICATIONS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2019-08-01 | — | — | WO | disclosed |
| WO-2019060432-A2 | GAPMERS AND METHODS OF USING THE SAME FOR TREATMENT OF MUSCULAR DYSTROPHY | CHILDREN'S NATIONAL MEDICAL CENTER (US) | 2019-03-28 | — | — | WO | disclosed |
| WO-2017136794-A1 | STRUCTURE-GUIDED CHEMICAL MODIFICATION OF GUIDE RNA AND ITS APPLICATIONS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2017-08-10 | — | — | WO | disclosed |
| WO-2017004279-A2 | COMPOSITIONS COMPRISING NUCLEIC ACIDS AND METHODS OF USING THE SAME | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2017-01-05 | — | — | WO | disclosed |
| US-8785157-B2 | Method for using ref protein as a targeted reca-dependent nuclease | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2014-07-22 | — | — | US | disclosed |
| EP-1651762-B1 | SMALL INTERFERING RNA SPECIFIC TO SUB-UNITS ALPHA, ALPHA' AND BETA OF THE KINASE PROTEIN CK2, AND THE APPLICATIONS OF THE SAME | COMMISSARIAT ENERGIE ATOMIQUE (FR) | 2013-11-20 | — | — | EP | disclosed |
| US-5340557-A | 32 P thiophosphate preparation | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1994-08-23 | — | — | US | disclosed |
| EP-0591316-A1 | ATP-DEPENDENT PROTEASE AND USE OF INHIBITORS FOR SAME IN THE TREATMENT OF CACHEXIA AND MUSCLE WASTING | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 1994-04-13 | — | — | EP | disclosed |
| EP-0573486-A1 | ?32 P THIOPHOSPHATE PREPARATION. | BRITISH TECH GROUP (GB) | 1993-12-15 | — | — | EP | disclosed |
| WO-1992020804-A1 | ATP-DEPENDENT PROTEASE AND USE OF INHIBITORS FOR SAME IN THE TREATMENT OF CACHEXIA AND MUSCLE WASTING | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 1992-11-26 | — | — | WO | disclosed |
| EP-0339686-B1 | NUCLEIC ACID HYBRIDIZATION ASSAY | MILES INC. (US) | 1992-09-16 | — | — | EP | disclosed |
| EP-0336454-B1 | NUCLEIC ACID HYBRIDIZATION ASSAY | MILES INC. (US) | 1992-09-16 | — | — | EP | disclosed |
| WO-1992014679-A1 | 32P THIOPHOSPHATE PREPARATION | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1992-09-03 | — | — | WO | disclosed |
| EP-0144913-A2 | Hybridization assay employing labeled probe and anti-hybrid | MILES INC. (US) | 1985-06-19 | — | — | EP | disclosed |