Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FASN | P49327 | 3/20 | 0.64 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.40 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.40 |
| ▸ | IMPDH2 | P12268 | 9/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PTGES | O14684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30151487 | 0.92 | FASN (0.77) | FASNPLA2G2APLA2G5IMPDH2FFAR1 | |
| SCHEMBL30550308 | 0.87 | FASN (0.69) | FASNPLA2G2APLA2G5IMPDH2FFAR1 | |
| SCHEMBL31578852 | 0.85 | FASN (0.69) | FASNPLA2G2APLA2G5IMPDH2FFAR1 | |
| SCHEMBL30550331 | 0.81 | FASN (0.59) | FASNPLA2G2APLA2G5IMPDH2FFAR1 | |
| SCHEMBL31232367 | 0.81 | FASN (0.59) | FASNPLA2G2APLA2G5IMPDH2FFAR1 | |
| SCHEMBL34468635 | 0.77 | FASN (0.55) | FASNPLA2G2APLA2G5IMPDH2 | |
| SCHEMBL29720143 | 0.76 | FASN (0.53) | FASNPLA2G2APLA2G5IMPDH2FFAR1 | |
| SCHEMBL30898483 | 0.76 | FASN (0.53) | FASNPLA2G2APLA2G5IMPDH2FFAR1 | |
| SCHEMBL31578934 | 0.75 | FASN (0.52) | FASNPLA2G2AL3MBTL1 | |
| SCHEMBL34468687 | 0.75 | FASN (0.52) | FASNPLA2G2APLA2G5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0585371-B1 | AROMATIC OLIGOMERIC COMPOUNDS USEFUL AS MIMICS OF BIOACTIVE MACROMOLECULES | RHONE POULENC RORER INTERNAT H (US) | 2002-04-17 | — | — | EP | disclosed |
| US-5571506-A | AROMATIC ALDEHYDE OLIGOMERS FOR TREATMENT OF CARDIOVASCULAR DISORDERS, BONE METABOLISM, ANTILIPEMIC AGENTS AND GASTROINTESTINAL DISORDERS | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1996-11-05 | — | — | US | disclosed |
| EP-0585371-A4 | AROMATIC OLIGOMERIC COMPOUNDS USEFUL AS MIMICS OF BIOACTIVE MACROMOLECULES | RHONE POULENC RORER INT (US) | 1994-07-13 | — | — | EP | disclosed |
| EP-0585371-A1 | AROMATIC OLIGOMERIC COMPOUNDS USEFUL AS MIMICS OF BIOACTIVE MACROMOLECULES | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1994-03-09 | — | — | EP | disclosed |
| WO-1992020350-A1 | AROMATIC OLIGOMERIC COMPOUNDS USEFUL AS MIMICS OF BIOACTIVE MACROMOLECULES | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1992-11-26 | — | — | WO | disclosed |