SCHEMBL7531246

SCHEMBL7531246

CC(C)C(C#N)C(=O)NC(N)=O

nearest known ligand 0.39

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 3/20 0.39
CRBN Q96SW2 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7755272 0.78 CRBN (0.39) DPP4CRBN
SCHEMBL16814565 0.75
SCHEMBL417121 0.73 SMN1; SMN2 (0.40) DPP4
SCHEMBL20068037 0.71 CRBN (0.41) DPP4CRBN
SCHEMBL3652416 0.70 CRBN (0.43) DPP4CRBN
Water SCHEMBL11371305 0.70 CRBN (0.43) CRBN
SCHEMBL9428999 0.69
SCHEMBL28728166 0.69 DPP4 (0.48) DPP4CRBN
SCHEMBL10575445 0.69 CRBN (0.42) DPP4CRBN
SCHEMBL28728167 0.69 DPP4 (0.48) DPP4CRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0911325-B1 Method for producing 5-isopropyluracil SUMIKA FINE CHEMICALS CO LTD (JP) 2002-04-17 EP claimed
US-6090970-A Production method of alkylated cyanoacetylurea SUMIKA FINE CHEMICALS CO., LTD. (JP) 2000-07-18 US claimed
EP-0965581-A1 Production method of alkylated cyanoacetylurea SUMIKA FINE CHEMICALS Co., Ltd. (JP) 1999-12-22 EP claimed
US-5914399-A Method for producing 5-isopropyluracil SUMIKA FINE CHEMICALS CO., LTD. (JP) 1999-06-22 US claimed
EP-0911325-A1 Method for producing 5-isopropyluracil SUMIKA FINE CHEMICALS Co., Ltd. (JP) 1999-04-28 EP claimed
JP-11189587-A None JP disclosed
JP-11130742-A None JP disclosed
EP-0911325-B1 Method for producing 5-isopropyluracil SUMIKA FINE CHEMICALS CO LTD (JP) 2002-04-17 EP disclosed
US-6090970-A Production method of alkylated cyanoacetylurea SUMIKA FINE CHEMICALS CO., LTD. (JP) 2000-07-18 US disclosed
EP-0965581-A1 Production method of alkylated cyanoacetylurea SUMIKA FINE CHEMICALS Co., Ltd. (JP) 1999-12-22 EP disclosed
JP-H11189587-A PRODUCTION OF 5-ISOPROPYLURACIL SUMIKA FINE CHEMICALS CO LTD 1999-07-13 JP disclosed
US-5914399-A Method for producing 5-isopropyluracil SUMIKA FINE CHEMICALS CO., LTD. (JP) 1999-06-22 US disclosed
US-5914399-A Method for producing 5-isopropyluracil SUMIKA FINE CHEMICALS CO., LTD. (JP) 1999-06-22 US disclosed
JP-H11130742-A PRODUCTION OF N-(2-CYANO-3-METHYLBUTYLOYL)UREA SUMIKA FINE CHEMICALS CO LTD 1999-05-18 JP disclosed
EP-0911325-A1 Method for producing 5-isopropyluracil SUMIKA FINE CHEMICALS Co., Ltd. (JP) 1999-04-28 EP disclosed
EP-0911325-A1 Method for producing 5-isopropyluracil SUMIKA FINE CHEMICALS Co., Ltd. (JP) 1999-04-28 EP disclosed