Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 10/20 | 0.64 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.46 |
| ▸ | CACNA1C | Q13936 | 6/20 | 0.45 |
| ▸ | CACNA1F | O60840 | 5/20 | 0.45 |
| ▸ | CACNA1D | Q01668 | 5/20 | 0.45 |
| ▸ | CACNA1S | Q13698 | 5/20 | 0.45 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7527534 | 0.93 | CACNA1B (0.72) | CACNA1BCACNA1CCACNA1FCACNA1DCACNA1S | |
| SCHEMBL7575655 | 0.92 | CACNA1B (0.54) | CACNA1BPDE1CCACNA1CCACNA1FCACNA1D | |
| SCHEMBL7525677 | 0.90 | CACNA1B (0.62) | CACNA1BCACNA1CCACNA1FCACNA1DCACNA1S | |
| SCHEMBL7533528 | 0.87 | CACNA1B (0.76) | CACNA1B | |
| SCHEMBL7531302 | 0.86 | CACNA1B (0.77) | CACNA1B | |
| SCHEMBL7529039 | 0.86 | CACNA1B (0.62) | CACNA1BPDE1CCACNA1CCACNA1FCACNA1D | |
| SCHEMBL7528201 | 0.85 | CACNA1B (0.61) | CACNA1BPDE1CCACNA1CCACNA1FCACNA1D | |
| SCHEMBL7532118 | 0.85 | CACNA1B (0.61) | CACNA1BPDE1C | |
| SCHEMBL7530718 | 0.85 | CACNA1B (0.59) | CACNA1BCACNA1CCACNA1FCACNA1DCACNA1S | |
| SCHEMBL7526364 | 0.85 | CACNA1B (0.64) | CACNA1BPDE1CCACNA1CKCNK2ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020147222-A1 | Dihydropyridine derivatives | AJINOMOTO CO. INC (JP) | 2002-10-10 | — | — | US | disclosed |
| EP-1191021-A1 | DIHYDROPYRIDINE DERIVATIVE | Ajinomoto Co., Inc. (JP) | 2002-03-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020147222-A1 | Dihydropyridine derivatives | CACNA1B, CACNA1D, CACNA1C | CACNA1B 1/4885PDE1C 141/4885CACNA1C 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.