Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCD | Q05655 | 1/20 | 1.00 |
| ▸ | CETP | P11597 | 1/20 | 0.91 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.78 |
| ▸ | NT5E | P21589 | 8/20 | 0.73 |
| ▸ | PRKCG | P05129 | 2/20 | 0.72 |
| ▸ | USP2 | O75604 | 1/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.69 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.69 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.69 |
| ▸ | ALB | P02768 | 1/20 | 0.69 |
| ▸ | POLB | P06746 | 1/20 | 0.69 |
| ▸ | GLI1 | P08151 | 1/20 | 0.69 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.69 |
| ▸ | DPP4 | P27487 | 1/20 | 0.69 |
| ▸ | RORC | P51449 | 1/20 | 0.69 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.69 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.69 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3784626 | 0.94 | PRKCD (0.89) | PRKCDCETPPTPN1NT5EPRKCG | |
| SCHEMBL12150557 | 0.92 | PRKCD (0.85) | PRKCDCETPPTPN1NT5EPRKCG | |
| SCHEMBL13259788 | 0.92 | PRKCD (0.85) | PRKCDCETPPTPN1NT5EPRKCG | |
| SCHEMBL15715885 | 0.91 | CETP (0.86) | PRKCDCETPPTPN1NT5EPRKCG | |
| SCHEMBL12150571 | 0.91 | PRKCD (0.83) | PRKCDCETPPTPN1NT5EPRKCG | |
| SCHEMBL2700741 | 0.91 | PRKCD (0.83) | PRKCDCETPPTPN1NT5EPRKCG | |
| SCHEMBL15478120 | 0.91 | PRKCD (0.83) | PRKCDCETPPTPN1NT5EPRKCG | |
| SCHEMBL12154546 | 0.91 | PRKCD (0.83) | PRKCDCETPPTPN1NT5EPRKCG | |
| SCHEMBL13259813 | 0.91 | PRKCD (0.83) | PRKCDCETPPTPN1NT5EPRKCG | |
| SCHEMBL12300364 | 0.90 | PRKCD (0.81) | PRKCDCETPPTPN1NT5EPRKCG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1189607-A2 | ANTI-TUMOR ACTIVITY OF VITAMIN E, CHOLESTEROL, TAXOL AND BETULINIC ACID DERIVATIVES | Washington State University Research Foundation (US) | 2002-03-27 | — | — | EP | disclosed |
| WO-2000059492-A2 | ANTI-TUMOR ACTIVITY OF VITAMIN E, CHOLESTEROL, TAXOL AND BETULINIC ACID DERIVATIVES | WASHINGTON STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2000-10-12 | — | — | WO | disclosed |