⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27638723 | 0.98 | — | — | |
| SCHEMBL3059696 | 0.74 | — | — | |
| SCHEMBL7525676 | 0.72 | GBA1 (0.42) | — | |
| SCHEMBL1188310 | 0.72 | — | — | |
| SCHEMBL26927 | 0.72 | — | — | |
| SCHEMBL6832473 | 0.72 | — | — | |
| SCHEMBL2164248 | 0.72 | — | — | |
| SCHEMBL1189011 | 0.72 | — | — | |
| SCHEMBL17477707 | 0.72 | GBA1 (0.37) | — | |
| SCHEMBL24186694 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4214712-A | — | — | None | — | — | JP | disclosed |
| EP-4201936-A1 | HETEROAROMATIC RING COMPOUND AS RET KINASE INHIBITOR, AND PREPARATION AND USE THEREOF | Jiangsu Chia Tai Fenghai Pharmaceutical Co., Ltd. (CN) | 2023-06-28 | — | — | EP | disclosed |
| CN-116333251-A | Polyurethane foam material and preparation method and application thereof | 北京化工大学 | 2023-06-27 | — | — | CN | disclosed |
| EP-3889154-A1 | HETEROCYCLIC COMPOUND INTERMEDIATE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Wuhan LL Science And Technology Development Co., Ltd. (CN) | 2021-10-06 | — | — | EP | disclosed |
| WO-2021136238-A1 | FUSED RING COMPOUND AND APPLICATION THEREOF | 武汉朗来科技发展有限公司 | 2021-07-08 | — | — | WO | disclosed |
| EP-3603644-A1 | PROLYL HYDROXYLASE INHIBITORS | Aerpio Therapeutics, Inc. (US) | 2020-02-05 | — | — | EP | disclosed |
| CN-105732459-B | Pyrrole amides class compound and preparation method thereof and purposes | 成都先导药物开发有限公司 | 2019-05-31 | — | — | CN | disclosed |
| CN-105899493-B | For inhibiting the active 1- of SHP2 (triazine -3- base/pyridazine -3- base)-piperazine (- piperazine) piperidine derivatives and combinations thereof | 诺华股份有限公司 | 2019-03-29 | — | — | CN | disclosed |
| CN-105814059-B | Imidazo pyrimidine derivatives as TNF active regulators | UCB生物制药私人有限公司 | 2018-04-03 | — | — | CN | disclosed |
| CN-105814046-B | Imidazopyridine derivatives as TNF active regulators | UCB生物制药私人有限公司 | 2018-01-30 | — | — | CN | disclosed |
| CN-105814046-A | Imidazopyridine derivatives as modulators of TNF activity | UCB生物制药私人有限公司 | 2016-07-27 | — | — | CN | disclosed |
| WO-2014144169-A1 | CARM1 INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2014-09-18 | — | — | WO | disclosed |
| EP-1187847-A1 | STREPTOGRAMIN DERIVATIVES, PREPARATION AND COMPOSITIONS CONTAINING THEM | Aventis Pharma S.A. (FR) | 2002-03-20 | — | — | EP | disclosed |
| WO-2001002427-A1 | STREPTOGRAMIN DERIVATIVES, PREPARATION AND COMPOSITIONS CONTAINING THEM | AVENTIS PHARMA S.A. (FR) | 2001-01-11 | — | — | WO | disclosed |
| US-5766505-A | MIXTURE OF POLYALKYLENE GLYCOL AND A GLYCOL ETHER | IDEMITSU KOSAN CO., LTD. (JP) | 1998-06-16 | — | — | US | disclosed |
| US-5240964-A | Adding piperazine catalyst with imidazole, triazine or amidine compound to create difference in gas evolution between inner and outer parts of plastic liquid | TOKYO SEAT CO., LTD. (JP) | 1993-08-31 | — | — | US | disclosed |
| JP-H04214712-A | PRODUCTION OF MOLDED PRODUCT OF URETHANE FOAM | TOKYO SEAT KK | 1992-08-05 | — | — | JP | disclosed |
| US-4663063-A | OIL AND FUEL ADDITIVES | THE LUBRIZOL CORPORATION (US) | 1987-05-05 | — | — | US | disclosed |
| EP-0203969-A1 | ALKYL PHENOL AND AMINO COMPOUND COMPOSITIONS AND TWO-CYCLE ENGINE OILS AND FUELS CONTAINING SAME. | LUBRIZOL CORP (US) | 1986-12-10 | — | — | EP | disclosed |
| WO-1986003220-A1 | ALKYL PHENOL AND AMINO COMPOUND COMPOSITIONS AND TWO-CYCLE ENGINE OILS AND FUELS CONTAINING SAME | THE LUBRIZOL CORPORATION (US) | 1986-06-05 | — | — | WO | disclosed |