SCHEMBL7533685

SCHEMBL7533685

C1=CCC(P(c2ccccc2)c2ccccc2)=C1.[Tl]

nearest known ligand 0.44

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
ESR1 P03372 2/20 0.35
ESR2 Q92731 2/20 0.35
DRD1 P21728 1/20 0.33
KDM4E B2RXH2 1/20 0.32
GAA P10253 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5732165 0.98 CYP3A4 (0.46) CYP3A4TDP1ESR1ESR2DRD1
SCHEMBL30995227 0.96 CYP3A4 (0.44) CYP3A4TDP1ESR1ESR2DRD1
SCHEMBL27564134 0.96 CYP3A4 (0.44) CYP3A4TDP1ESR1ESR2DRD1
SCHEMBL29960204 0.96 CYP3A4 (0.44) CYP3A4TDP1ESR1ESR2DRD1
SCHEMBL31070079 0.96 CYP3A4 (0.44) CYP3A4TDP1ESR1ESR2DRD1
Hydrochloric Acid SCHEMBL23273899 0.96 CYP3A4 (0.44) CYP3A4TDP1ESR1ESR2DRD1
SCHEMBL31281697 0.96 CYP3A4 (0.44) CYP3A4TDP1ESR1ESR2DRD1
SCHEMBL29802768 0.96 CYP3A4 (0.44) CYP3A4TDP1ESR1ESR2DRD1
Hydrochloric Acid SCHEMBL20700137 0.94 CYP3A4 (0.42) CYP3A4TDP1ESR1ESR2DRD1
Hydrochloric Acid SCHEMBL31152752 0.92 CYP3A4 (0.41) CYP3A4TDP1ESR1ESR2DRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1019422-B1 PHOSPHINE-SUBSTITUTED COBALTICINIUM SALTS, PRODUCTION THEREOF, AND USE OF THE SAME AS CONSTITUENTS OF CATALYSTS CELANESE CHEM EUROPE GMBH (DE) 2002-05-02 EP disclosed
EP-1019422-A1 PHOSPHINE-SUBSTITUTED COBALTICINIUM SALTS, PRODUCTION THEREOF, AND USE OF THE SAME AS CONSTITUENTS OF CATALYSTS Celanese Chemicals Europe GmbH (DE) 2000-07-19 EP disclosed
WO-1999016776-A1 PHOSPHINE-SUBSTITUTED COBALTICINIUM SALTS, PRODUCTION THEREOF, AND USE OF THE SAME AS CONSTITUENTS OF CATALYSTS CELANESE CHEMICALS EUROPE GMBH (DE) 1999-04-08 WO disclosed