Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19756664 | 0.81 | SLC6A4 (0.48) | SLC6A2SLC6A4SLC6A3HTR2C | |
| Hydrochloric Acid SCHEMBL6596636 | 0.79 | SLC6A2 (0.40) | SLC6A2SLC6A4SLC6A3HTR2C | |
| Hydrochloric Acid SCHEMBL6596641 | 0.79 | SLC6A2 (0.40) | SLC6A2SLC6A4SLC6A3HTR2C | |
| Hydrochloric Acid SCHEMBL6596637 | 0.79 | SLC6A2 (0.40) | SLC6A2SLC6A4SLC6A3HTR2C | |
| SCHEMBL22720938 | 0.78 | SLC6A4 (0.41) | SLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL29732264 | 0.77 | SLC6A4 (0.40) | SLC6A2SLC6A4SLC6A3HTR2C | |
| Hydrochloric Acid SCHEMBL22721034 | 0.77 | SLC6A4 (0.40) | SLC6A2SLC6A4SLC6A3HTR2C | |
| Hydrochloric Acid SCHEMBL6598367 | 0.77 | SLC6A4 (0.40) | SLC6A2SLC6A4SLC6A3HTR2C | |
| Hydrochloric Acid SCHEMBL6596988 | 0.76 | SLC6A4 (0.38) | SLC6A2SLC6A4SLC6A3HTR2C | |
| Hydrochloric Acid SCHEMBL6596986 | 0.76 | SLC6A4 (0.38) | SLC6A2SLC6A4SLC6A3HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100501-A4 | PYRROLIDINE AND PYRROLINE DERIVATIVES HAVING EFFECTS ON SEROTONIN RELATED SYSTEMS | LILLY CO ELI (US) | 2002-12-04 | — | — | EP | disclosed |
| EP-1100501-A1 | PYRROLIDINE AND PYRROLINE DERIVATIVES HAVING EFFECTS ON SEROTONIN RELATED SYSTEMS | ELI LILLY AND COMPANY (US) | 2001-05-23 | — | — | EP | disclosed |
| WO-2000000196-A1 | PYRROLIDINE AND PYRROLINE DERIVATIVES HAVING EFFECTS ON SEROTONIN RELATED SYSTEMS | ELI LILLY AND COMPANY (US) | 2000-01-06 | — | — | WO | disclosed |