Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10321770 | 0.76 | GRM2 (0.56) | GRM2 | |
| SCHEMBL10320966 | 0.76 | GRM2 (0.74) | GRM2KCNH2 | |
| SCHEMBL10320451 | 0.75 | GRM2 (0.59) | GRM2 | |
| SCHEMBL10321964 | 0.73 | GRM2 (0.60) | GRM2KCNH2 | |
| SCHEMBL753388 | 0.73 | GRM2 (0.48) | GRM2 | |
| SCHEMBL7861343 | 0.72 | GRM2 (0.55) | GRM2 | |
| SCHEMBL19633012 | 0.71 | GRM2 (1.00) | GRM2KCNH2 | |
| SCHEMBL10320958 | 0.70 | GRM2 (0.52) | GRM2 | |
| SCHEMBL742373 | 0.70 | GRM2 (0.60) | GRM2 | |
| SCHEMBL738170 | 0.70 | GRM2 (0.63) | GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2430031-A1 | 1,2,4-TRIAZOLO[4,3-A]PYRIDINE DERIVATIVES AND THEIR USE AS POSITIVE ALLOSTERIC MODULATORS OF MGLUR2 RECEPTORS | Janssen Pharmaceuticals Inc. (US) | 2012-03-21 | — | — | EP | disclosed |
| WO-2010130422-A1 | 1,2,4-TRIAZOLO[4,3-A]PYRIDINE DERIVATIVES AND THEIR USE AS POSITIVE ALLOSTERIC MODULATORS OF MGLUR2 RECEPTORS | ORTHO-MCNEIL-JANSSEN PHARMACEUTICALS, INC (US) | 2010-11-18 | — | — | WO | disclosed |