SCHEMBL7534307

SCHEMBL7534307

O=C1c2cccc(NCCS(=O)(=O)F)c2C(=O)c2cccc(NCCS(=O)(=O)F)c21

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NSD2 O96028 2/20 0.55
FGB P02675 1/20 0.55
MMP14 P50281 1/20 0.55
MEN1 O00255 6/20 0.50
KMT2A Q03164 6/20 0.50
MAPT P10636 4/20 0.50
POLB P06746 3/20 0.50
EGFR P00533 2/20 0.50
MAPK1 P28482 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
BLM P54132 2/20 0.50
LMNA P02545 2/20 0.50
HTT P42858 2/20 0.50
ALDH1A1 P00352 1/20 0.50
RAD52 P43351 1/20 0.50
RECQL P46063 1/20 0.50
NPSR1 Q6W5P4 1/20 0.50
RAB9A P51151 2/20 0.46
PABPC1 P11940 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7529391 0.95 MAPT (0.57) NSD2FGBMMP14MEN1KMT2A
SCHEMBL7524671 0.86 MEN1 (0.59) NSD2FGBMMP14MEN1KMT2A
SCHEMBL7529170 0.80 MEN1 (0.52) NSD2FGBMMP14MEN1KMT2A
SCHEMBL8698507 0.79 MEN1 (0.55) NSD2FGBMMP14MEN1KMT2A
SCHEMBL9357997 0.79 NSD2 (0.77) NSD2FGBMMP14MEN1KMT2A
SCHEMBL6372565 0.79 NSD2 (0.58) NSD2FGBMMP14MEN1KMT2A
SCHEMBL8707598 0.76 NSD2 (0.63) NSD2FGBMMP14MEN1KMT2A
SCHEMBL375063 0.76 NSD2 (0.77) NSD2FGBMMP14MEN1KMT2A
SCHEMBL6372408 0.76 NSD2 (0.63) NSD2FGBMMP14MEN1KMT2A
SCHEMBL20334284 0.76 NSD2 (0.63) NSD2FGBMMP14MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0743994-B1 ANTHRAQUINONE DYES CONTAINING A FLUOROSULPHONYL GROUP AND USE THEREOF DYSTAR TEXTILFARBEN GMBH & CO (DE) 2002-04-17 EP disclosed
US-5759211-A COLORING SYNTHETIC TEXTILE OR FIBER BLEND ZENECA LIMITED (GB) 1998-06-02 US disclosed
US-5759211-A COLORING SYNTHETIC TEXTILE OR FIBER BLEND ZENECA LIMITED (GB) 1998-06-02 US disclosed
EP-0743994-A1 ANTHRAQUINONE DYES CONTAINING A FLUOROSULPHONYL GROUP AND USE THEREOF ZENECA LIMITED (GB) 1996-11-27 EP disclosed
EP-0743994-A1 ANTHRAQUINONE DYES CONTAINING A FLUOROSULPHONYL GROUP AND USE THEREOF ZENECA LIMITED (GB) 1996-11-27 EP disclosed
WO-1995021958-A1 ANTHRAQUINONE DYES CONTAINING A FLUOROSULPHONYL GROUP AND USE THEREOF ZENECA LIMITED (GB) 1995-08-17 WO disclosed
WO-1995021958-A1 ANTHRAQUINONE DYES CONTAINING A FLUOROSULPHONYL GROUP AND USE THEREOF ZENECA LIMITED (GB) 1995-08-17 WO disclosed