Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17997783 | 0.84 | — | — | |
| SCHEMBL2119425 | 0.72 | FFAR3 (0.40) | FFAR3 | |
| SCHEMBL21950919 | 0.67 | FFAR3 (0.36) | FFAR3 | |
| SCHEMBL21950922 | 0.67 | FFAR3 (0.36) | FFAR3 | |
| Cyclohexane SCHEMBL1079006 | 0.65 | FFAR3 (0.41) | FFAR3 | |
| SCHEMBL3923364 | 0.65 | — | — | |
| SCHEMBL1245323 | 0.62 | — | — | |
| SCHEMBL1062689 | 0.62 | FFAR3 (0.38) | FFAR3 | |
| SCHEMBL17997784 | 0.62 | MEN1 (0.34) | — | |
| SCHEMBL788930 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2430013-A1 | HETEROARYL COMPOUNDS AS PIKK INHIBITORS | Amgen, Inc (US) | 2012-03-21 | — | — | EP | claimed |
| WO-2010132598-A1 | HETEROARYL COMPOUNDS AS PIKK INHIBITORS | AMGEN INC. (US) | 2010-11-18 | — | — | WO | claimed |
| EP-2430013-A1 | HETEROARYL COMPOUNDS AS PIKK INHIBITORS | Amgen, Inc (US) | 2012-03-21 | — | — | EP | disclosed |
| WO-2010132598-A1 | HETEROARYL COMPOUNDS AS PIKK INHIBITORS | AMGEN INC. (US) | 2010-11-18 | — | — | WO | disclosed |