Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 16/20 | 1.00 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.47 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6383425 | 1.00 | FOLH1 (1.00) | FOLH1GRM3NAALAD2 | |
| SCHEMBL16529159 | 0.94 | FOLH1 (1.00) | FOLH1GRM3NAALAD2 | |
| SCHEMBL787800 | 0.94 | FOLH1 (1.00) | FOLH1GRM3NAALAD2 | |
| SCHEMBL10348904 | 0.87 | FOLH1 (0.80) | FOLH1GRM3NAALAD2 | |
| SCHEMBL3517121 | 0.87 | FOLH1 (0.76) | FOLH1 | |
| SCHEMBL2058227 | 0.85 | FOLH1 (1.00) | FOLH1GRM3NAALAD2 | |
| SCHEMBL3521470 | 0.85 | FOLH1 (0.77) | FOLH1 | |
| SCHEMBL3515562 | 0.85 | FOLH1 (0.73) | FOLH1 | |
| SCHEMBL28267581 | 0.85 | FOLH1 (0.73) | FOLH1GRM3NAALAD2 | |
| SCHEMBL16178767 | 0.84 | FOLH1 (0.72) | FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1202717-A2 | NAALADASE INHIBITORS IN ANXIETY AND MEMORY DISORDERS | GUILFORD PHARMACEUTICALS INC. (US) | 2002-05-08 | — | — | EP | disclosed |
| WO-2001001974-A2 | NAALADASE INHIBITORS IN ANXIETY AND MEMORY DISORDERS | GUILFORD PHARMACEUTICALS INC. (US) | 2001-01-11 | — | — | WO | disclosed |