Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7537203 | 1.00 | SLC18A3 (0.51) | SLC18A3ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL7537075 | 0.93 | SLC18A3 (0.57) | SLC18A3ALDH1A1TSHRSMN1; SMN2HPGD | |
| SCHEMBL7537080 | 0.93 | SLC18A3 (0.57) | SLC18A3ALDH1A1TSHRSMN1; SMN2HPGD | |
| SCHEMBL7537073 | 0.93 | SLC18A3 (0.57) | SLC18A3ALDH1A1TSHRSMN1; SMN2HPGD | |
| SCHEMBL7537082 | 0.89 | SLC18A3 (0.56) | SLC18A3TSHR | |
| SCHEMBL7537087 | 0.89 | SLC18A3 (0.56) | SLC18A3TSHR | |
| SCHEMBL7537077 | 0.89 | SLC18A3 (0.56) | SLC18A3TSHR | |
| SCHEMBL7537930 | 0.89 | SLC18A3 (0.52) | SLC18A3ALDH1A1 | |
| SCHEMBL7537938 | 0.89 | SLC18A3 (0.52) | SLC18A3ALDH1A1 | |
| SCHEMBL7539958 | 0.87 | SLC18A3 (0.57) | SLC18A3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1205473-A1 | VESAMICOL PIPERAZINE DERIVATIVES AND DRUGS CONTAINING THE SAME | DAIICHI RADIOISOTOPE LABORATORIES, LTD. (JP) | 2002-05-15 | — | — | EP | disclosed |