Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5631511 | 0.76 | EDNRA (0.64) | EDNRBEDNRA | |
| SCHEMBL5107783 | 0.73 | EDNRB (0.64) | EDNRBEDNRA | |
| SCHEMBL7480038 | 0.71 | ADORA1 (0.37) | EDNRBEDNRA | |
| SCHEMBL5097996 | 0.70 | EDNRB (0.56) | EDNRBEDNRA | |
| SCHEMBL7481070 | 0.69 | EDNRB (0.63) | EDNRB | |
| SCHEMBL15334043 | 0.66 | PDPK1 (0.37) | — | |
| SCHEMBL1457182 | 0.66 | EDNRA (0.64) | EDNRBEDNRA | |
| SCHEMBL30835141 | 0.66 | EDNRA (0.64) | EDNRBEDNRA | |
| SCHEMBL4426215 | 0.64 | EDNRB (0.59) | EDNRBEDNRA | |
| SCHEMBL14380661 | 0.64 | EDNRB (0.33) | EDNRBEDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0959072-B1 | Sulfonamide derivative and process for preparing the same | TANABE SEIYAKU CO (JP) | 2002-09-25 | — | — | EP | disclosed |
| EP-0959072-A1 | Sulfonamide derivative and process for preparing the same | TANABE SEIYAKU CO., LTD. (JP) | 1999-11-24 | — | — | EP | disclosed |
| US-5739333-A | 4-SULFONAMIDO-6-ARYLOXY OR -AMINOALKYLENEOXY,-AMINO, OR -THIOPYRIMIDINES; ENDOLTHELIN ANTAGONISTS; HYPOTENSIVE AND ULCER AGENTS; ASTHMA; RAYNAUD DISEASE; CARDIOVASCULAR DISORDERS | TANABE SEIYAKU CO., LTD. (JP) | 1998-04-14 | — | — | US | disclosed |
| US-5728706-A | ENDOTHELIN ANTAGONISTS | TANABE SEIYAKU CO., LTD. (JP) | 1998-03-17 | — | — | US | disclosed |
| EP-0658548-B1 | Benzenesulfonamide derivative and process for preparing thereof | TANABE SEIYAKU CO (JP) | 1997-11-19 | — | — | EP | disclosed |
| US-5589478-A | ENDOTHELIN ANTAGONISTS | TANABE SEIYAKU CO., LTD. (JP) | 1996-12-31 | — | — | US | disclosed |
| EP-0743307-A1 | Sulfonamide derivative and process for preparing the same | TANABE SEIYAKU CO., LTD. (JP) | 1996-11-20 | — | — | EP | disclosed |
| EP-0658548-A1 | Benzenesulfonamide derivative and process for preparing thereof | TANABE SEIYAKU CO., LTD. (JP) | 1995-06-21 | — | — | EP | disclosed |