Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.53 |
| ▸ | MEN1 | O00255 | 6/20 | 0.53 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7538963 | 1.00 | SLC18A3 (0.55) | SLC18A3KMT2AMEN1HTR1AALDH1A1 | |
| SCHEMBL7537678 | 1.00 | SLC18A3 (0.55) | SLC18A3KMT2AMEN1HTR1AALDH1A1 | |
| SCHEMBL7538957 | 1.00 | SLC18A3 (0.55) | SLC18A3KMT2AMEN1HTR1AALDH1A1 | |
| SCHEMBL7541826 | 0.81 | SLC18A3 (0.60) | SLC18A3KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL7536876 | 0.81 | SLC18A3 (0.60) | SLC18A3KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL7537244 | 0.81 | SLC18A3 (0.60) | SLC18A3KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL7537232 | 0.81 | SLC18A3 (0.60) | SLC18A3KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL7536879 | 0.81 | SLC18A3 (0.60) | SLC18A3KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL7537234 | 0.81 | SLC18A3 (0.60) | SLC18A3KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL7536882 | 0.81 | SLC18A3 (0.60) | SLC18A3KMT2AMEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1205473-A1 | VESAMICOL PIPERAZINE DERIVATIVES AND DRUGS CONTAINING THE SAME | DAIICHI RADIOISOTOPE LABORATORIES, LTD. (JP) | 2002-05-15 | — | — | EP | disclosed |