SCHEMBL7537784

SCHEMBL7537784

CC1CCC(CN)(Cc2nsc(=O)[nH]2)C1.CC1CCC(CN)(Cc2nsc(=O)[nH]2)C1

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TP53 P04637 2/20 0.33
MDM2 Q00987 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5439978 1.00 TP53 (0.33) TP53MDM2
SCHEMBL5381269 1.00 TP53 (0.33) TP53MDM2
SCHEMBL5381275 1.00 TP53 (0.33) TP53MDM2
SCHEMBL5389105 1.00 TP53 (0.33) TP53MDM2
SCHEMBL5393822 1.00 TP53 (0.33) TP53MDM2
SCHEMBL5438119 0.92 CYP1A2 (0.38) TP53MDM2
SCHEMBL5438116 0.92 CYP1A2 (0.38) TP53MDM2
SCHEMBL7046799 0.90 CYP1A2 (0.36)
SCHEMBL5395942 0.83 TP53 (0.33) TP53MDM2
SCHEMBL5398446 0.83 TP53 (0.33) TP53MDM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2002036118-A2 HETEROCYCLIC DERIVATIVES USEFUL AS PHARMACEUTICAL AGENTS WARNER-LAMBERT COMPANY LLC (US) 2002-05-10 WO disclosed