SCHEMBL7538003

SCHEMBL7538003

C1=CCC2CCC([Zr]C3CCC4CC=CC=C43)C2=C1.C=C(C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1,1-Dichloroethene SCHEMBL9054669 0.90
Ethylene SCHEMBL3669698 0.90
SCHEMBL2474821 0.89
SCHEMBL6432168 0.70
SCHEMBL813889 0.70
Hydrochloric Acid SCHEMBL6432319 0.69
SCHEMBL22584 0.69
SCHEMBL8104299 0.69 CYP2D6 (0.30)
Fluoride Ion SCHEMBL5281606 0.68
SCHEMBL7108852 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0805824-B1 A SUPPORTED CATALYTIC ACTIVATOR GRACE W R & CO (US) 2002-04-24 EP claimed
US-20020006863-A1 HALOGENATED SUPPORTS AND SUPPORTED ACTIVATORS W.R. GRACE & CO.-CONN. 2002-01-17 US claimed
US-20010018395-A1 HALOGENATED SUPPORTS AND SUPPORTED ACTIVATORS W.R. GRACE & CO.-CONN. 2001-08-30 US claimed
EP-0830385-B1 HALOGENATED SUPPORTS AND SUPPORTED ACTIVATORS GRACE W R & CO (US) 2000-12-27 EP claimed
EP-0830385-A1 HALOGENATED SUPPORTS AND SUPPORTED ACTIVATORS W.R. Grace & Co.-Conn. (US) 1998-03-25 EP claimed
WO-1996040796-A1 HALOGENATED SUPPORTS AND SUPPORTED ACTIVATORS W.R. GRACE & CO.-CONN. (US) 1996-12-19 WO claimed
US-6432863-B2 FOR TRANSITION METAL CATALYST W. R. GRACE & CO.-CONN. 2002-08-13 US disclosed
US-6403518-B2 MADE BY REACTING AN INORGANIC OR POLYMERIC CARRIER CONTAINING REACTIVE FUNCTIONALITIES WITH A HALOGENATED ORGANIC IN THE PRESENCE OF A BASE; TRANSITION METAL CATALYSTS FURTHER SUPPORTED ON THE CARRIER W. R. GRACE & CO.-CONN. 2002-06-11 US disclosed
EP-0805824-B1 A SUPPORTED CATALYTIC ACTIVATOR GRACE W R & CO (US) 2002-04-24 EP disclosed
US-20020006863-A1 HALOGENATED SUPPORTS AND SUPPORTED ACTIVATORS W.R. GRACE & CO.-CONN. 2002-01-17 US disclosed
US-20010018395-A1 HALOGENATED SUPPORTS AND SUPPORTED ACTIVATORS W.R. GRACE & CO.-CONN. 2001-08-30 US disclosed
EP-0830385-B1 HALOGENATED SUPPORTS AND SUPPORTED ACTIVATORS GRACE W R & CO (US) 2000-12-27 EP disclosed
US-5939347-A Supported catalytic activator W.R. GRACE & CO. -CONN. (US) 1999-08-17 US disclosed
US-5885924-A REACTING A CARRIER CONTAINING REACTIVE FUNCTIONALITIES, E.G., HYDROXYL CONTAINING SILICA, WITH HALOGENATED ORGANIC COMPOUNDS, E.G., FLUOROSUBSTITUTED PHENOLS, IN THE PRESENCE OF A BASE W. R. GRACE & CO.-CONN. (US) 1999-03-23 US disclosed
WO-1996040796-A1 HALOGENATED SUPPORTS AND SUPPORTED ACTIVATORS W.R. GRACE & CO.-CONN. (US) 1996-12-19 WO disclosed