Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.55 |
| ▸ | FAAH | O00519 | 4/20 | 0.48 |
| ▸ | CES1 | P23141 | 2/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | PLA2G4C | Q9UP65 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7538172 | 0.95 | EPHX1 (0.63) | EPHX1FAAHCES1EPHX2ALDH1A1 | |
| SCHEMBL7543543 | 0.95 | EPHX1 (0.63) | EPHX1FAAHCES1EPHX2ALDH1A1 | |
| SCHEMBL7539129 | 0.92 | EPHX1 (0.65) | EPHX1FAAHCES1ALDH1A1MEN1 | |
| SCHEMBL7542360 | 0.92 | EPHX1 (0.65) | EPHX1FAAHCES1ALDH1A1MEN1 | |
| SCHEMBL7535887 | 0.87 | EPHX1 (0.63) | EPHX1FAAHCES1EPHX2ALDH1A1 | |
| SCHEMBL7542534 | 0.87 | EPHX1 (0.63) | EPHX1FAAHCES1EPHX2ALDH1A1 | |
| SCHEMBL7539126 | 0.86 | EPHX1 (0.75) | EPHX1ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL7535768 | 0.86 | EPHX1 (0.75) | EPHX1ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL7536111 | 0.86 | EPHX1 (0.75) | EPHX1ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL7542355 | 0.86 | EPHX1 (0.75) | EPHX1ALDH1A1MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1200454-A1 | BISPLATINUM COMPLEXES ACTIVE THROUGH THE ORAL ROUTE | Novuspharma S.p.A. (IT) | 2002-05-02 | — | — | EP | disclosed |
| WO-2001009149-A1 | BISPLATINUM COMPLEXES ACTIVE THROUGH THE ORAL ROUTE | NOVUSPHARMA S.P.A. (IT) | 2001-02-08 | — | — | WO | disclosed |