SCHEMBL753828

SCHEMBL753828

COC(=O)CCCCCCCCCC[Si](C)(C)OC

nearest known ligand 0.56

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.56
LMNA P02545 3/20 0.50
ALDH1A1 P00352 1/20 0.50
RECQL P46063 1/20 0.45
EPHX2 P34913 5/20 0.42
KMT2A Q03164 1/20 0.42
HPGD P15428 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.40
GLA P06280 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31503128 0.91 TSHR (0.61) TSHRLMNAALDH1A1RECQLEPHX2
SCHEMBL6373627 0.88 TSHR (0.56) TSHRLMNAALDH1A1RECQLEPHX2
SCHEMBL13431383 0.85 TSHR (0.58) TSHRLMNAALDH1A1RECQLEPHX2
SCHEMBL30775458 0.84 TSHR (0.52) TSHRLMNAALDH1A1RECQLEPHX2
SCHEMBL9913181 0.84 TSHR (0.52) TSHRLMNAALDH1A1RECQLEPHX2
SCHEMBL30985266 0.83 TSHR (0.56) TSHRLMNAALDH1A1RECQLEPHX2
SCHEMBL19770540 0.83 TSHR (0.56) TSHRLMNAALDH1A1RECQLEPHX2
SCHEMBL5972801 0.83 TSHR (0.56) TSHRLMNAALDH1A1RECQLEPHX2
SCHEMBL11128153 0.83 TSHR (0.56) TSHRLMNAALDH1A1RECQLEPHX2
SCHEMBL3502791 0.82 TSHR (0.82) TSHRLMNAALDH1A1RECQLEPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250326204-A1 FLOW CELL SYSTEMS AND METHODS NAUTILUS SUBSIDIARY INC (US) 2025-10-23 US disclosed
US-12377635-B2 Flow cell systems and methods NAUTILUS SUBSIDIARY, INC. (US) 2025-08-05 US disclosed
US-12306093-B2 Methods and systems for integrated on-chip single-molecule detection NAUTILUS SUBSIDIARY, INC. (US) 2025-05-20 US disclosed
US-20250075101-A1 SURFACE TREATMENT Interphase Materials, Inc (US) 2025-03-06 US disclosed
US-12146071-B2 Surface treatment INTERPHASE MATERIALS INC. (US) 2024-11-19 US disclosed
US-20230256425-A1 INORGANIC POROUS SUBSTRATE, INORGANIC POROUS SUPPORT, AND NUCLEIC ACID PRODUCTION METHOD SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2023-08-17 US disclosed
US-20230221243-A1 METHODS AND SYSTEMS FOR INTEGRATED ON-CHIP SINGLE-MOLECULE DETECTION NAUTILUS SUBSIDIARY, INC. 2023-07-13 US disclosed
US-20230213438-A1 METHODS AND SYSTEMS FOR INTEGRATED ON-CHIP SINGLE-MOLECULE DETECTION NAUTILUS SUBSIDIARY, INC. 2023-07-06 US disclosed
CN-115461143-A Compositions, methods, and systems for sample processing 10X基因组学有限公司 2022-12-09 CN disclosed
US-20220379582-A1 FLOW CELL SYSTEMS AND METHODS NAUTILUS SUBSIDIARY, INC. 2022-12-01 US disclosed
US-20130177770-A1 BONDING METHOD, BONDABILITY IMPROVING AGENT, SURFACE MODIFICATION METHOD, SURFACE MODIFYING AGENT, AND NOVEL COMPOUND SULFUR CHEMICAL INSTITUTE INCORPORATED (JP) 2013-07-11 US disclosed
EP-2503330-A2 Multicapillary device for sample preparation Chromba, Inc. (US) 2012-09-26 EP disclosed
EP-2319956-B1 Metallizing a zone of porous silicon by in situ reduction and application in a fuel cell COMMISSARIAT ENERGIE ATOMIQUE (FR) 2012-03-21 EP disclosed
US-20110263838-A1 MULTICAPILLARY DEVICE FOR SAMPLE PREPARATION BELOV YURI P 2011-10-27 US disclosed
US-20110130616-A1 Magnetically Responsive Nanoparticle Therapeutic Constructs and Methods of Making and Using SWR&D INC. 2011-06-02 US disclosed
EP-2319956-A1 Metallizing a zone of porous silicon by in situ reduction and application in a fuel cell Commissariat à l'Énergie Atomique et aux Énergies Alternatives (FR) 2011-05-11 EP disclosed
US-20110086165-A1 METALLIZATION OF A POROUS SILICON ZONE BY IN SITU REDUCTION AND APPLICATION TO A FUEL CELL COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2011-04-14 US disclosed
WO-2011042620-A1 FORMATION OF METAL PARTICLES ON A SOLID OXIDE SUBSTRATE HAVING TWO SEPARATE GRAFTED CHEMICAL FUNCTIONS COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2011-04-14 WO disclosed
US-20100055416-A1 COMPOSITE AND MANUFACTURING METHOD THEREOF SAMSUNG ELECTRO-MECHANICS CO., LTD. (KR) 2010-03-04 US disclosed
US-20070017870-A1 Multicapillary device for sample preparation BIOEDGE, LLC 2007-01-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230256425-A1 INORGANIC POROUS SUBSTRATE, INORGANIC POROUS SUPPORT, AND NUCLEIC ACID PRODUCTION METHOD DNMT3L, FBL, SIK1 TSHR 4846/4885LMNA 373/4885ALDH1A1 3252/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.