Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 11/20 | 0.55 |
| ▸ | ICAM1 | P05362 | 11/20 | 0.55 |
| ▸ | ITGAL | P20701 | 11/20 | 0.55 |
| ▸ | ITGA4 | P13612 | 5/20 | 0.43 |
| ▸ | ITGB1 | P05556 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7538530 | 0.94 | ITGB2 (0.48) | ITGB2ICAM1ITGALITGA4ITGB1 | |
| SCHEMBL7544812 | 0.90 | ITGB2 (0.56) | ITGB2ICAM1ITGALITGA4ITGB1 | |
| SCHEMBL7547460 | 0.90 | ITGB2 (0.56) | ITGB2ICAM1ITGALITGA4ITGB1 | |
| SCHEMBL7545077 | 0.89 | ITGB2 (0.51) | ITGB2ICAM1ITGALITGA4ITGB1 | |
| SCHEMBL7544703 | 0.89 | ITGB2 (0.51) | ITGB2ICAM1ITGALITGA4ITGB1 | |
| SCHEMBL7539842 | 0.89 | ITGB2 (0.51) | ITGB2ICAM1ITGALITGA4ITGB1 | |
| SCHEMBL7544261 | 0.89 | ITGB2 (0.51) | ITGB2ICAM1ITGALITGA4ITGB1 | |
| SCHEMBL6807195 | 0.88 | KMT2A (0.47) | ITGB2ICAM1ITGALITGA4ITGB1 | |
| SCHEMBL7540780 | 0.88 | ITGB2 (0.45) | ITGB2ICAM1ITGALKMT2AMEN1 | |
| SCHEMBL7541577 | 0.88 | ITGB2 (0.55) | ITGB2ICAM1ITGALITGA4ITGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1209147-A1 | CARBOXYLIC ACID DERIVATIVES AND ADHESION MOLECULE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2002-05-29 | — | — | EP | disclosed |