Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 4/20 | 0.48 |
| ▸ | ICAM1 | P05362 | 4/20 | 0.48 |
| ▸ | ITGAL | P20701 | 4/20 | 0.48 |
| ▸ | TACR1 | P25103 | 1/20 | 0.44 |
| ▸ | GPR139 | Q6DWJ6 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GPR132 | Q9UNW8 | 4/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7540043 | 0.92 | TACR1 (0.46) | ITGB2ICAM1ITGALTACR1GPR139 | |
| SCHEMBL7545919 | 0.91 | ITGB2 (0.49) | ITGB2ICAM1ITGALTACR1L3MBTL1 | |
| SCHEMBL7539253 | 0.91 | ITGB1 (0.49) | ITGB2ICAM1ITGALTACR1GPR139 | |
| SCHEMBL7540060 | 0.90 | ITGB2 (0.51) | ITGB2ICAM1ITGALTACR1L3MBTL1 | |
| SCHEMBL7539177 | 0.88 | ITGB2 (0.49) | ITGB2ICAM1ITGALTACR1L3MBTL1 | |
| SCHEMBL7545879 | 0.88 | ITGB2 (0.49) | ITGB2ICAM1ITGALL3MBTL1TP53 | |
| SCHEMBL7563730 | 0.87 | ITGB2 (0.61) | ITGB2ICAM1ITGALL3MBTL1TP53 | |
| SCHEMBL7547460 | 0.86 | ITGB2 (0.56) | ITGB2ICAM1ITGALL3MBTL1TP53 | |
| SCHEMBL7544812 | 0.86 | ITGB2 (0.56) | ITGB2ICAM1ITGALL3MBTL1TP53 | |
| SCHEMBL7539088 | 0.86 | ITGB2 (0.52) | ITGB2ICAM1ITGALTACR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1209147-A1 | CARBOXYLIC ACID DERIVATIVES AND ADHESION MOLECULE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2002-05-29 | — | — | EP | disclosed |