Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 6/20 | 0.44 |
| ▸ | ITGA4 | P13612 | 6/20 | 0.44 |
| ▸ | GRN | P28799 | 1/20 | 0.44 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | FPR2 | P25090 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ANPEP | P15144 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7538889 | 1.00 | ITGB1 (0.44) | ITGB1ITGA4GRNSORT1ALDH1A1 | |
| SCHEMBL7546106 | 0.93 | ITGB1 (0.49) | ITGB1ITGA4FPR2MAPT | |
| SCHEMBL7546113 | 0.93 | ITGB1 (0.49) | ITGB1ITGA4FPR2MAPT | |
| SCHEMBL7540162 | 0.92 | ITGB1 (0.46) | ITGB1ITGA4FPR2MAPK1MAPT | |
| SCHEMBL7540159 | 0.92 | ITGB1 (0.46) | ITGB1ITGA4FPR2MAPK1MAPT | |
| SCHEMBL7539509 | 0.92 | ITGB1 (0.44) | ITGB1ITGA4FPR2MAPTANPEP | |
| SCHEMBL7539506 | 0.92 | ITGB1 (0.44) | ITGB1ITGA4FPR2MAPTANPEP | |
| SCHEMBL7545874 | 0.90 | ANPEP (0.53) | ITGB1ITGA4ALDH1A1LMNAFPR2 | |
| SCHEMBL7545877 | 0.90 | ANPEP (0.53) | ITGB1ITGA4ALDH1A1LMNAFPR2 | |
| SCHEMBL7538590 | 0.90 | GRN (0.45) | ITGB1ITGA4GRNSORT1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1209147-A1 | CARBOXYLIC ACID DERIVATIVES AND ADHESION MOLECULE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2002-05-29 | — | — | EP | disclosed |