Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 5/20 | 0.50 |
| ▸ | ICAM1 | P05362 | 5/20 | 0.50 |
| ▸ | ITGAL | P20701 | 5/20 | 0.50 |
| ▸ | TACR1 | P25103 | 1/20 | 0.45 |
| ▸ | ITGB1 | P05556 | 11/20 | 0.44 |
| ▸ | ITGA4 | P13612 | 10/20 | 0.44 |
| ▸ | ITGB7 | P26010 | 2/20 | 0.44 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.44 |
| ▸ | ITGAV | P06756 | 1/20 | 0.43 |
| ▸ | BBOX1 | O75936 | 2/20 | 0.43 |
| ▸ | UBASH3B | Q8TF42 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7541565 | 0.94 | UBASH3B (0.48) | ITGB2ICAM1ITGALTACR1ITGB1 | |
| SCHEMBL7539022 | 0.94 | UBASH3B (0.48) | ITGB2ICAM1ITGALTACR1ITGB1 | |
| SCHEMBL7542020 | 0.94 | ITGB2 (0.53) | ITGB2ICAM1ITGALITGB1ITGA4 | |
| SCHEMBL7546236 | 0.94 | ITGB2 (0.53) | ITGB2ICAM1ITGALITGB1ITGA4 | |
| SCHEMBL7541192 | 0.93 | ITGB1 (0.47) | ITGB2ICAM1ITGALITGB1ITGA4 | |
| SCHEMBL7540086 | 0.93 | ITGB2 (0.49) | ITGB2ICAM1ITGALITGB1ITGA4 | |
| SCHEMBL7538745 | 0.93 | ITGB2 (0.45) | ITGB2ICAM1ITGALTACR1ITGB1 | |
| SCHEMBL7547093 | 0.91 | ITGB2 (0.49) | ITGB2ICAM1ITGALITGB1ITGA4 | |
| SCHEMBL7542573 | 0.91 | ITGB2 (0.49) | ITGB2ICAM1ITGALITGB1ITGA4 | |
| SCHEMBL7541285 | 0.91 | ITGB2 (0.48) | ITGB2ICAM1ITGALITGB1ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1209147-A1 | CARBOXYLIC ACID DERIVATIVES AND ADHESION MOLECULE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2002-05-29 | — | — | EP | disclosed |