Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 5/20 | 0.55 |
| ▸ | ICAM1 | P05362 | 5/20 | 0.55 |
| ▸ | ITGAL | P20701 | 5/20 | 0.55 |
| ▸ | ITGB1 | P05556 | 15/20 | 0.53 |
| ▸ | ITGA4 | P13612 | 15/20 | 0.53 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.49 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7540127 | 1.00 | ITGB2 (0.55) | ITGB2ICAM1ITGALITGB1ITGA4 | |
| SCHEMBL7542691 | 0.93 | ITGB2 (0.55) | ITGB2ICAM1ITGALITGB1ITGA4 | |
| SCHEMBL7541035 | 0.93 | ITGB2 (0.56) | ITGB2ICAM1ITGALITGB1ITGA4 | |
| SCHEMBL7542573 | 0.93 | ITGB2 (0.49) | ITGB2ICAM1ITGALITGB1ITGA4 | |
| SCHEMBL7547093 | 0.93 | ITGB2 (0.49) | ITGB2ICAM1ITGALITGB1ITGA4 | |
| SCHEMBL7544012 | 0.92 | ITGB2 (0.60) | ITGB2ICAM1ITGALITGB1ITGA4 | |
| SCHEMBL7540625 | 0.92 | ITGB2 (0.60) | ITGB2ICAM1ITGALITGB1ITGA4 | |
| SCHEMBL7542050 | 0.92 | ITGB2 (0.60) | ITGB2ICAM1ITGALITGB1ITGA4 | |
| SCHEMBL7541919 | 0.92 | ITGB2 (0.60) | ITGB2ICAM1ITGALITGB1ITGA4 | |
| SCHEMBL7542020 | 0.90 | ITGB2 (0.53) | ITGB2ICAM1ITGALITGB1ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1209147-A1 | CARBOXYLIC ACID DERIVATIVES AND ADHESION MOLECULE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2002-05-29 | — | — | EP | disclosed |