Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 20/20 | 0.82 |
| ▸ | PDE4B | Q07343 | 20/20 | 0.82 |
| ▸ | PDE4C | Q08493 | 20/20 | 0.82 |
| ▸ | PDE4D | Q08499 | 20/20 | 0.82 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.59 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7539899 | 1.00 | PDE4A (0.82) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL7539894 | 1.00 | PDE4A (0.82) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL7136848 | 0.90 | PDE4B (1.00) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL7136851 | 0.90 | PDE4B (1.00) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL7136855 | 0.90 | PDE4B (1.00) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL5564874 | 0.87 | PDE4D (1.00) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL5564875 | 0.87 | PDE4D (1.00) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL5564872 | 0.87 | PDE4D (1.00) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL7147540 | 0.85 | PDE4A (0.90) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL7147538 | 0.85 | PDE4A (0.90) | PDE4APDE4BPDE4CPDE4DPDE3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999031071-A1 | NEW PHTHALAZINONES | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1999-06-24 | — | — | WO | disclosed |