Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 7/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7540271 | 1.00 | SLC18A3 (0.47) | SLC18A3NPSR1POLBSMN1; SMN2MAPK1 | |
| SCHEMBL7540266 | 1.00 | SLC18A3 (0.47) | SLC18A3NPSR1POLBSMN1; SMN2MAPK1 | |
| SCHEMBL7540315 | 0.88 | SLC18A3 (0.46) | SLC18A3NPSR1POLBSMN1; SMN2MAPK1 | |
| SCHEMBL7540313 | 0.88 | SLC18A3 (0.46) | SLC18A3NPSR1POLBSMN1; SMN2MAPK1 | |
| SCHEMBL7537520 | 0.88 | SLC18A3 (0.46) | SLC18A3NPSR1POLBSMN1; SMN2MAPK1 | |
| SCHEMBL7540353 | 0.85 | MAPT (0.52) | SLC18A3POLBSMN1; SMN2MAPK1ALDH1A1 | |
| SCHEMBL7540356 | 0.85 | MAPT (0.52) | SLC18A3POLBSMN1; SMN2MAPK1ALDH1A1 | |
| SCHEMBL17491563 | 0.82 | SLC18A3 (0.59) | SLC18A3 | |
| SCHEMBL7537155 | 0.80 | SLC18A3 (0.62) | SLC18A3 | |
| SCHEMBL7537160 | 0.80 | SLC18A3 (0.62) | SLC18A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1205473-A1 | VESAMICOL PIPERAZINE DERIVATIVES AND DRUGS CONTAINING THE SAME | DAIICHI RADIOISOTOPE LABORATORIES, LTD. (JP) | 2002-05-15 | — | — | EP | disclosed |