SCHEMBL7540825

SCHEMBL7540825

OC(=S)CC(Cc1ccccc1)C(O)=S

nearest known ligand 0.52

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.52
CPA1 P15085 9/20 0.50
CPA3 P15088 3/20 0.50
CPB1 P15086 1/20 0.50
CPB2 Q96IY4 1/20 0.50
FOLH1 Q04609 2/20 0.46
MME P08473 1/20 0.43
SLC1A3 P43003 1/20 0.42
SLC1A2 P43004 1/20 0.42
SLC1A1 P43005 1/20 0.42
EPHX1 P07099 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7540835 0.84 CPA1 (0.72) CYP1A2CPA1CPA3CPB1CPB2
SCHEMBL6154517 0.81 CYP1A2 (0.55) CYP1A2CPA1CPA3CPB1CPB2
SCHEMBL21758201 0.81 CYP1A2 (0.55) CYP1A2CPA1CPA3CPB1CPB2
SCHEMBL6154524 0.81 CYP1A2 (0.55) CYP1A2CPA1CPA3CPB1CPB2
SCHEMBL6155724 0.81 CYP1A2 (0.55) CYP1A2CPA1CPA3CPB1CPB2
SCHEMBL11239071 0.80 TSHR (0.59) CYP1A2CPA1CPA3CPB1CPB2
SCHEMBL11262596 0.80 TSHR (0.59) CYP1A2CPA1CPA3CPB1CPB2
SCHEMBL11129057 0.80 TSHR (0.59) CYP1A2CPA1CPA3CPB1CPB2
SCHEMBL8925188 0.79 CYP1A2 (0.52) CYP1A2CPA1CPA3CPB1CPB2
SCHEMBL27878857 0.79 CYP1A2 (0.57) CYP1A2CPA1CPA3CPB1CPB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1207909-A2 METHOD FOR COUPLING MOLECULES MEDICAL RESEARCH COUNCIL (GB) 2002-05-29 EP disclosed
WO-2001015737-A2 METHOD FOR COUPLING MOLECULES MEDICAL RESEARCH COUNCIL (GB) 2001-03-08 WO disclosed