Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 17/20 | 0.70 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.35 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14423060 | 0.74 | TYMP (0.47) | TYMPSMN1; SMN2 | |
| SCHEMBL17551856 | 0.73 | MAPT (0.50) | TYMP | |
| SCHEMBL2884681 | 0.72 | TYMP (0.53) | TYMP | |
| SCHEMBL2672686 | 0.69 | TYMP (0.75) | TYMP | |
| SCHEMBL5259684 | 0.69 | TYMP (0.52) | TYMP | |
| SCHEMBL16174525 | 0.68 | TYMP (0.48) | TYMP | |
| SCHEMBL11762589 | 0.68 | DHODH (0.55) | — | |
| SCHEMBL20799748 | 0.68 | TYMP (0.50) | TYMP | |
| SCHEMBL12850282 | 0.68 | TYMP (0.62) | TYMPSMN1; SMN2 | |
| SCHEMBL28448729 | 0.67 | TYMP (0.56) | TYMP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119775260-A | Pyrimidine-2, 4 (1H, 3H) -dione compounds, preparation method, pharmaceutical composition and application thereof | 中国医学科学院药物研究所 | 2025-04-08 | — | — | CN | disclosed |
| EP-0748316-B1 | PYRIMIDINE ACYCLONUCLEOSIDE DERIVATIVES | SUNKYONG IND LTD (KR) | 2002-05-08 | — | — | EP | disclosed |
| EP-0736015-B1 | ANTIVIRAL 2,4-PYRIMIDINDIONE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | KOREA RES INST CHEM TECH (KR) | 2001-03-07 | — | — | EP | disclosed |
| US-5889013-A | REACTING AN URACIL COMPOUND WITH N, O-BIS/TRIMETHYLSILYL/ACETAMIDE FOLLOWED BY TETRABUTYLAMMONIUM IODIDE AND CHLOROMETHYL ETHER COMPOUND AND THEN REACTING WITH ARYL SELENOL IN A BASE | SUNKYONG INDUSTRIES CO., INC. (KR) | 1999-03-30 | — | — | US | disclosed |
| US-5747500-A | VIRICIDES FOR AIDS | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1998-05-05 | — | — | US | disclosed |
| EP-0748316-A1 | PYRIMIDINE ACYCLONUCLEOSIDE DERIVATIVES | SUNKYONG INDUSTRIES CO., LTD. (KR) | 1996-12-18 | — | — | EP | disclosed |
| EP-0736015-A1 | NOVEL ANTIVIRAL 2,4-PYRIMIDINEDIONE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1996-10-09 | — | — | EP | disclosed |
| WO-1995023138-A1 | PYRIMIDINE ACYCLONUCLEOSIDE DERIVATIVES | SUNKYONG INDUSTRIES CO., LTD. (KR) | 1995-08-31 | — | — | WO | disclosed |
| WO-1995018109-A1 | NOVEL ANTIVIRAL 2,4-PYRIMIDINEDIONE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1995-07-06 | — | — | WO | disclosed |
| US-4182859-A | Process for the preparation of 2'-deoxyribofuranosyl nucleosides | ROBUGEN GMBH PHARMACEUTISCHE FABRIK (DE) | 1980-01-08 | — | — | US | disclosed |